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Cellosaurus HepG2-NIAS (CVCL_A7DQ)

[Text version]

Cell line name HepG2-NIAS
Accession CVCL_A7DQ
Resource Identification Initiative To cite this cell line use: HepG2-NIAS (RRID:CVCL_A7DQ)
Comments Population: Caucasian.
Characteristics: Can not only rapidly activate hepatic functions such as albumin secretion, urea synthesis and CYP3A4 activity but also induce the formation of bile canaliculus-like structures by utilizing a collagen vitrigel membrane as a culture substratum (RCB).
Derived from sampling site: Liver.
Sequence variations
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0027 (Hep-G2)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line

Oshikata-Miyazaki A., Takezawa T.
Characteristics of HepG2-NIAS cells (RCB4679).
Tissue Cult. Res. Commun. 37:72-72(2018)

Cell line collections RCB; RCB4679
Encyclopedic resources Wikidata; Q107115337
Entry history
Entry creation20-May-2021
Last entry update23-Sep-2021
Version number2