| Cell line name | HepG2-NIAS |
|---|---|
| Accession | CVCL_A7DQ |
| Resource Identification Initiative | To cite this cell line use: HepG2-NIAS (RRID:CVCL_A7DQ) |
| Comments | Population: Caucasian. Characteristics: Can not only rapidly activate hepatic functions such as albumin secretion, urea synthesis and CYP3A4 activity but also induce the formation of bile canaliculus-like structures by utilizing a collagen vitrigel membrane as a culture substratum (RCB). Derived from sampling site: Liver. |
| Sequence variations | Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line). |
| Disease | Hepatoblastoma (NCIt: C3728) Hepatoblastoma (ORDO: Orphanet_449) |
| Species of origin | Homo sapiens (Human)
(NCBI Taxonomy: 9606)
|
| Hierarchy | Parent: CVCL_0027 (Hep-G2) |
| Sex of cell | Male |
| Age at sampling | 15Y |
| Category | Cancer cell line |
| Publications | CLPUB00634 |
| Cross-references | |
| Cell line collections | RCB; RCB4679 |
| Other | Wikidata; Q107115337 |
| Entry history | |
| Entry creation | 20-May-2021 |
| Last entry update | 23-Sep-2021 |
| Version number | 2 |