ID   HepG2-NIAS
AC   CVCL_A7DQ
DR   RCB; RCB4679
DR   Wikidata; Q107115337
RX   CelloPub=CLPUB00634;
CC   Population: Caucasian.
CC   Characteristics: Can not only rapidly activate hepatic functions such as albumin secretion, urea synthesis and CYP3A4 activity but also induce the formation of bile canaliculus-like structures by utilizing a collagen vitrigel membrane as a culture substratum (RCB).
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Derived from sampling site: Liver.
DI   NCIt; C3728; Hepatoblastoma
DI   ORDO; Orphanet_449; Hepatoblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens
HI   CVCL_0027 ! Hep-G2
SX   Male
AG   15Y
CA   Cancer cell line
DT   Created: 20-05-21; Last updated: 23-09-21; Version: 2
//
RX   CelloPub=CLPUB00634;
RA   Oshikata-Miyazaki A., Takezawa T.;
RT   "Characteristics of HepG2-NIAS cells (RCB4679).";
RL   Tissue Cult. Res. Commun. 37:72-72(2018).
//