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Cellosaurus MIN6 rho0 (CVCL_A7QH)

Cell line name MIN6 rho0
Synonyms rho0 MIN6
Accession CVCL_A7QH
Resource Identification Initiative To cite this cell line use: MIN6 rho0 (RRID:CVCL_A7QH)
Comments Characteristics: Cell line devoid of mitochondrial DNA (rho0). Obtained by growth of parental cell line with bis-4-piperidyle-dichloride (PubMed=8824267).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Pancreas, islets of Langerhans; UBERON=UBERON_0000006.
Cell type: Pancreatic beta cell; CL=CL_0000169.
Disease Mouse insulinoma (NCIt: C34053)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6 IT6 transgenic.
Hierarchy Parent: CVCL_0431 (MIN6)
Sex of cell Sex unspecified
Age at sampling 13W
Category Transformed cell line
Publications

PubMed=8824267; DOI=10.1074/jbc.271.42.26194
Soejima A., Inoue K., Takai D., Kaneko M., Ishihara H., Oka Y., Hayashi J.-i.
Mitochondrial DNA is required for regulation of glucose-stimulated insulin secretion in a mouse pancreatic beta cell line, MIN6.
J. Biol. Chem. 271:26194-26199(1996)

Cross-references
Encyclopedic resources Wikidata; Q107116373
Entry history
Entry creation20-May-2021
Last entry update29-Jun-2023
Version number5