ID   A549-hACE2 [BEI resources]
AC   CVCL_A7UV
DR   BEI_Resources; NR-53821
DR   cancercelllines; CVCL_A7UV
DR   Wikidata; Q107113334
CC   Group: SARS-CoV-2 research cell line.
CC   From: Baric R.; Department of Epidemiology, University of North Carolina at Chapel Hill; Chapel Hill; USA.
CC   Population: Caucasian.
CC   Characteristics: Expresses ACE2 under the control of the EF1a promoter (BEI_Resources=NR-53821).
CC   Sequence variation: Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
CC   Transfected with: HGNC; 13557; ACE2.
CC   Transfected with: UniProtKB; P0C2P0; Aspergillus terreus blasticidin-S deaminase (Bsd).
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
DI   NCIt; C3512; Lung adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0023 ! A-549
SX   Male
AG   58Y
CA   Cancer cell line
DT   Created: 20-05-21; Last updated: 05-10-23; Version: 5
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