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Cellosaurus NUC12N2 (CVCL_A8GI)

[Text version]

Cell line name NUC12N2
Accession CVCL_A8GI
Resource Identification Initiative To cite this cell line use: NUC12N2 (RRID:CVCL_A8GI)
Comments Population: Japanese.
Transfected with: HGNC; 16412; NLRC4 (with p.Leu152_Ala1024del, CARD domain, C12N2 construct).
Transfected with: HGNC; 5331; NOD2 (with p.Met1_Ala216del, NACHT+LRR domains, C12N2 construct).
Disease Gastric signet ring cell adenocarcinoma (NCIt: C5250)
Derived from metastatic site: Paragastric lymph node.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_3082 (NUGC-4)
Sex of cell Female
Age at sampling 35Y
Category Cancer cell line
Publications

PubMed=16964285; DOI=10.1038/sj.onc.1209965
Hasegawa M., Kawase K., Inohara N., Imamura R., Yeh W.-C., Kinoshita T., Suda T.
Mechanism of ASC-mediated apoptosis: bid-dependent apoptosis in type II cells.
Oncogene 26:1748-1756(2007)

PubMed=20500518; DOI=10.1111/j.1349-7006.2010.01610.x
Motani K., Kawase K., Imamura R., Kinoshita T., Kushiyama H., Suda T.
Activation of ASC induces apoptosis or necrosis, depending on the cell type, and causes tumor eradication.
Cancer Sci. 101:1822-1827(2010)

Cross-references
Encyclopedic resources Wikidata; Q107116596
Entry history
Entry creation20-May-2021
Last entry update23-Sep-2021
Version number2