ID   NUC12N2
AC   CVCL_A8GI
DR   Wikidata; Q107116596
RX   PubMed=16964285;
RX   PubMed=20500518;
CC   Population: Japanese.
CC   Transfected with: HGNC; 16412; NLRC4 (with p.Leu152_Ala1024del, CARD domain, C12N2 construct).
CC   Transfected with: HGNC; 5331; NOD2 (with p.Met1_Ala216del, NACHT+LRR domains, C12N2 construct).
CC   Derived from site: Metastatic; Paragastric lymph node; UBERON=UBERON_8480059.
DI   NCIt; C5250; Gastric signet ring cell adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_3082 ! NUGC-4
SX   Female
AG   35Y
CA   Cancer cell line
DT   Created: 20-05-21; Last updated: 29-06-23; Version: 4
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RX   PubMed=16964285; DOI=10.1038/sj.onc.1209965;
RA   Hasegawa M., Kawase K., Inohara N., Imamura R., Yeh W.-C.,
RA   Kinoshita T., Suda T.;
RT   "Mechanism of ASC-mediated apoptosis: bid-dependent apoptosis in type
RT   II cells.";
RL   Oncogene 26:1748-1756(2007).
//
RX   PubMed=20500518; DOI=10.1111/j.1349-7006.2010.01610.x;
RA   Motani K., Kawase K., Imamura R., Kinoshita T., Kushiyama H., Suda T.;
RT   "Activation of ASC induces apoptosis or necrosis, depending on the
RT   cell type, and causes tumor eradication.";
RL   Cancer Sci. 101:1822-1827(2010).
//