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Cellosaurus LCSBi006-A (CVCL_A8MD)

[Text version]
Cell line name LCSBi006-A
Synonyms ND34267-LRRK2/PARK8-G2019S-clone 8; ND34267-LRRK2-clone 8; ND34267-clone 8; ND34267-8
Accession CVCL_A8MD
Resource Identification Initiative To cite this cell line use: LCSBi006-A (RRID:CVCL_A8MD)
Comments From: Luxembourg Centre for Systems Biomedicine; Belvaux; Luxembourg.
Population: Caucasian.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; 18618; LRRK2; Simple; p.Gly2019Ser (c.6055G>A); ClinVar=VCV000001940; Zygosity=Heterozygous (PubMed=34736041).
Disease Parkinson disease 8, autosomal dominant (NCIt: C198605)
Hereditary late-onset Parkinson disease (ORDO: Orphanet_411602)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_EZ01 (ND34267)
Sex of cell Male
Age at sampling 63Y
Category Induced pluripotent stem cell
Publications

PubMed=34736041; DOI=10.1016/j.scr.2021.102569
Novak G., Finkbeiner S., Skibinski G., Skupin A.
Generation of two human induced pluripotent stem cell lines from fibroblasts of unrelated Parkinson's patients carrying the G2019S mutation in the LRRK2 gene (LCSBi005, LCSBi006).
Stem Cell Res. 57:102569-102569(2021)

Cross-references
Cell line databases/resources hPSCreg; LCSBi006-A
Biological sample resources BioSamples; SAMEA10585991
Encyclopedic resources Wikidata; Q108820777
Entry history
Entry creation23-Sep-2021
Last entry update30-Jan-2024
Version number5