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Cellosaurus STBCi026-A-1 (CVCL_A8Z8)

Cell line name STBCi026-A-1
Synonyms SFC840-03-03 LRRK2-/- D10
Accession CVCL_A8Z8
Resource Identification Initiative To cite this cell line use: STBCi026-A-1 (RRID:CVCL_A8Z8)
Comments From: StemBANCC; Oxford; United Kingdom.
Knockout cell: Method=CRISPR/Cas9; HGNC; 18618; LRRK2.
Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
Cell type: Fibroblast of skin; CL=CL_0002620.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_RB85 (STBCi026-A)
Sex of cell Female
Age at sampling 67Y
Category Induced pluripotent stem cell
Publications

PubMed=32359446; DOI=10.1016/j.stemcr.2020.04.001
Lee H., Flynn R., Sharma I., Haberman E., Carling P.J., Nicholls F.J., Stegmann M., Vowles J., Haenseler W., Wade-Martins R., James W.S., Cowley S.A.
LRRK2 is recruited to phagosomes and co-recruits RAB8 and RAB10 in human pluripotent stem cell-derived macrophages.
Stem Cell Reports 14:940-955(2020)

Cross-references
Cell line collections (Providers) EBiSC; STBCi026-A-1
ECACC; 66541205 - Discontinued
Cell line databases/resources hPSCreg; STBCi026-A-1
Biological sample resources BioSamples; SAMEA5859479
Encyclopedic resources Wikidata; Q102114944
Entry history
Entry creation29-Oct-2020
Last entry update30-Jan-2024
Version number8