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Cellosaurus CUi001-A-1 (CVCL_A8ZC)

[Text version]

Cell line name CUi001-A-1
Synonyms WB1-10 WRNKI-Cre18
Accession CVCL_A8ZC
Resource Identification Initiative To cite this cell line use: CUi001-A-1 (RRID:CVCL_A8ZC)
Comments From: Chiba University; Chiba; Japan.
Population: Japanese.
Derived from sampling site: Peripheral blood.
Sequence variations
  • Mutation; HGNC; 12791; WRN; Simple; p.Lys1046fs*14 (c.3139-1G>C) (IVS25-1G>C); ClinVar=VCV000005447; Zygosity=Heterozygous; Note=Splice acceptor mutation (PubMed=34087989).
  • Mutation; HGNC; 12791; WRN; Simple_corrected; p.Lys1046fs*14 (c.3139-1G>C) (IVS25-1G>C); ClinVar=VCV000005447; Zygosity=Heterozygous; Note=Splice acceptor mutation. By CRISPR/Cas9 (PubMed=34087989).
Disease Werner syndrome (NCIt: C3447)
Werner syndrome (ORDO: Orphanet_902)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_A8ZB (CUi001-A)
Sex of cell Male
Age at sampling 52Y
Category Induced pluripotent stem cell
STR profile Source(s): PubMed=34087989

Markers:
AmelogeninX,Y
CSF1PO12
D1S165617
D2S44111,13
D2S133819,22
D3S135815,16
D5S8189,10
D7S82010
D8S117911,14
D10S124812,13
D12S39118,20
D13S31710,12
D16S5399,10
D18S5119,20
D19S43314,15.2
D21S1129
D22S104511,17
DYS39110
FGA19,26
SE3317,21
TH019
TPOX11,12
vWA14,17

Run an STR similarity search on this cell line
Publications

PubMed=34087989; DOI=10.1016/j.scr.2021.102360
Kato H., Maezawa Y., Ouchi Y., Takayama N., Sone M., Sone K., Takada-Watanabe A., Tsujimura K., Koshizaka M., Nagasawa S., Saitoh H., Ohtaka M., Nakanishi M., Tahara H., Shimamoto A., Iwama A., Eto K., Yokote K.
Generation of disease-specific and CRISPR/Cas9-mediated gene-corrected iPS cells from a patient with adult progeria Werner syndrome.
Stem Cell Res. 53:102360-102360(2021)

Cross-references
Cell line databases/resources hPSCreg; CUi001-A-1
Encyclopedic resources Wikidata; Q108820094
Entry history
Entry creation23-Sep-2021
Last entry update16-Dec-2021
Version number2