| Cell line name | NF-kappaB reporter (Luc)-Jurkat |
|---|---|
| Accession | CVCL_A9P4 |
| Resource Identification Initiative | To cite this cell line use: NF-kappaB reporter (Luc)-Jurkat (RRID:CVCL_A9P4) |
| Comments | Characteristics: Expression of the luciferase gene is driven by four copies of the NF-kappaB response element located upstream of a minimal TATA promoter. Transfected with: UniProtKB; P08659; Firefly luciferase. Transfected with: UniProtKB; P00552; Transposon Tn5 neo. Derived from sampling site: Peripheral blood. |
| Sequence variations | Heterozygous for BAX p.Glu41Argfs*19 (c.121delG) (ClinVar=VCV000009512) (from parent cell line).Heterozygous for BAX p.Glu41Glyfs*33 (c.121dupG) (ClinVar=VCV000009511) (from parent cell line).Heterozygous for FBXW7 p.Arg505Cys (c.1513C>T) (ClinVar=VCV000069961) (from parent cell line).Heterozygous for INPP5D p.Gln345Ter (c.1033C>T) (from parent cell line).Heterozygous for INPP5D c.1097+1065_1097+1112del47 (from parent cell line).Homozygous for MSH2 p.Arg711Ter (c.2131C>T) (ClinVar=VCV000090903) (from parent cell line).Homozygous for MSH6 p.Phe1088Serfs*2 (c.3261delC) (ClinVar=VCV000089363) (from parent cell line).Heterozygous for SYK p.Met34Hisfs*3 (c.98_99insG) (from parent cell line).Heterozygous for TP53 p.Arg196Ter (c.586C>T) (ClinVar=VCV000043589) (from parent cell line). |
| Disease | Childhood T acute lymphoblastic leukemia (NCIt: C7953) Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861) |
| Species of origin | Homo sapiens (Human)
(NCBI Taxonomy: 9606)
|
| Hierarchy | Parent: CVCL_0367 (Jurkat E6.1) |
| Sex of cell | Male |
| Age at sampling | 14Y |
| Category | Cancer cell line |
| Web pages | https://bpsbioscience.com/nf-kb-luciferase-reporter-luc-jurkat-recombinant-cell-line |
| Cross-references | |
| Other | Wikidata; Q102114597 |
| Entry history | |
| Entry creation | 29-Oct-2020 |
| Last entry update | 12-Jan-2021 |
| Version number | 2 |