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Cellosaurus HPSI1113i-wetu_2 (CVCL_AI06)

Cell line name HPSI1113i-wetu_2
Synonyms WTSIi227-A
Accession CVCL_AI06
Resource Identification Initiative To cite this cell line use: HPSI1113i-wetu_2 (RRID:CVCL_AI06)
Comments From: Cambridge BioResource; Cambridge; United Kingdom.
From: Wellcome Trust Sanger Institute; Hinxton; United Kingdom.
Population: Caucasian; British.
Omics: Deep exome analysis.
Omics: Deep proteome analysis.
Omics: DNA methylation analysis.
Omics: Genome sequenced.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_VN07 (WTSIi227-A-1)
Originate from same individual CVCL_JQ29 ! HPSI1113i-wetu_1
CVCL_JQ30 ! HPSI1113i-wetu_3
Sex of cell Female
Age at sampling 55-59Y
Category Induced pluripotent stem cell
Publications

PubMed=28489815; DOI=10.1038/nature22403
Kilpinen H., Goncalves A., Leha A., Afzal V., Alasoo K., Ashford S., Bala S., Bensaddek D., Casale F.P., Culley O.J., Danecek P., Faulconbridge A., Harrison P.W., Kathuria A., McCarthy D., McCarthy S.A., Meleckyte R., Memari Y., Moens N., Soares F., Mann A., Streeter I., Agu C.A., Alderton A., Nelson R., Harper S., Patel M.J., White A., Patel S.R., Clarke L., Halai R., Kirton C.M., Kolb-Kokocinski A., Beales P., Birney E., Danovi D., Lamond A.I., Ouwehand W.H., Vallier L., Watt F.M., Durbin R., Stegle O., Gaffney D.J.
Common genetic variation drives molecular heterogeneity in human iPSCs.
Nature 546:370-375(2017)

PubMed=30784590; DOI=10.1016/j.celrep.2019.01.094
Vigilante A., Laddach A., Moens N., Meleckyte R., Leha A., Ghahramani A., Culley O.J., Kathuria A., Hurling C., Vickers A., Wiseman E., Tewary M., Zandstra P.W., Durbin R., Fraternali F., Stegle O., Birney E., Luscombe N.M., Danovi D., Watt F.M.
Identifying extrinsic versus intrinsic drivers of variation in cell behavior in human iPSC lines from healthy donors.
Cell Rep. 26:2078-2087.e3(2019)

Cross-references
Cell line collections (Providers) ECACC; 77650026
Cell line databases/resources HipSci; HPSI1113i-wetu_2
hPSCreg; WTSIi227-A
Biological sample resources BioSamples; SAMEA2464814
Encyclopedic resources Wikidata; Q54891667
Gene expression databases ArrayExpress; E-MTAB-4057
Entry history
Entry creation23-Feb-2016
Last entry update29-Jun-2023
Version number15