ID   HEK 293 STF
AC   CVCL_AQ26
SY   STF; Super TOP-FLASH; SuperTopFlash
DR   ATCC; CRL-3249
DR   Kerafast; EJH014
DR   Wikidata; Q54882278
RX   PubMed=15035989;
CC   Characteristics: Responds to activation of the canonical Wnt signaling pathway by increasing expression of firefly luciferase. Luciferase reporter gene expression is under the control of a promoter with 7 LEF/TCF binding sites (PubMed=15035989).
CC   Transfected with: UniProtKB; P08659; Firefly luciferase.
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 28285; Adenovirus 5.
CC   Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
ST   Source(s): ATCC
ST   Amelogenin: X
ST   CSF1PO: 11,12
ST   D13S317: 12,14
ST   D16S539: 9
ST   D5S818: 8,9
ST   D7S820: 11,12
ST   TH01: 7,9.3
ST   TPOX: 11
ST   vWA: 16,19
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0045 ! HEK293
SX   Female
AG   Fetus
CA   Transformed cell line
DT   Created: 02-05-16; Last updated: 05-10-23; Version: 11
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RX   PubMed=15035989; DOI=10.1016/S0092-8674(04)00216-8;
RA   Xu Q., Wang Y.-S., Dabdoub A., Smallwood P.M., Williams J., Woods C.,
RA   Kelley M.W., Jiang L., Tasman W., Zhang K., Nathans J.;
RT   "Vascular development in the retina and inner ear: control by norrin
RT   and frizzled-4, a high-affinity ligand-receptor pair.";
RL   Cell 116:883-895(2004).
//