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Cellosaurus HCEC 1CT (CVCL_AQ45)

[Text version]

Cell line name HCEC 1CT
Synonyms hCEC-1CT; Human Colonic Epithelial Cells 1 transduced with CDK4 and Telomerase; 1CT
Accession CVCL_AQ45
Resource Identification Initiative To cite this cell line use: HCEC 1CT (RRID:CVCL_AQ45)
Comments Transfected with: HGNC; 1773; CDK4.
Transfected with: HGNC; 11730; TERT.
Omics: Deep exome analysis.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_AV01 (HCEC 1CTA)CVCL_AV02 (HCEC 1CTP)CVCL_AV03 (HCEC 1CTR)
CVCL_AQ46 (HCEC 1CT+7)
Sex of cell Male
Category Telomerase immortalized cell line
STR profile Source(s): PubMed=27047802

Markers:
AmelogeninX,Y
CSF1PO10,12
D5S81811,14
D7S8209,11
D13S31712,13
D16S53910,11
D21S1128
TH019.3
TPOX11
vWA16,18

Run an STR similarity search on this cell line
Web pages http://www.evercyte.com/hcec-1ct-166.html
Publications

PubMed=19962984; DOI=10.1053/j.gastro.2009.11.052
Roig A.I., Eskiocak U., Hight S.K., Kim S.B., Delgado O., Souza R.F., Spechler S.J., Wright W.E., Shay J.W.
Immortalized epithelial cells derived from human colon biopsies express stem cell markers and differentiate in vitro.
Gastroenterology 138:1012-1021(2010)

PubMed=21527559; DOI=10.1158/0008-5472.CAN-11-0794
Eskiocak U., Kim S.B., Ly P., Roig A.I., Biglione S., Komurov K., Cornelius C., Wright W.E., White M.A., Shay J.W.
Functional parsing of driver mutations in the colorectal cancer genome reveals numerous suppressors of anchorage-independent growth.
Cancer Res. 71:4359-4365(2011)

PubMed=21472139; DOI=10.1593/neo.101580
Ly P., Eskiocak U., Kim S.B., Roig A.I., Hight S.K., Lulla D.R., Zou Y.S., Batten K., Wright W.E., Shay J.W.
Characterization of aneuploid populations with trisomy 7 and 20 derived from diploid human colonic epithelial cells.
Neoplasia 13:348-357(2011)

PubMed=25923178; DOI=10.1186/1471-2164-16-S1-S8
Zhang L., Kim S., Jia G., Buhmeida A., Dallol A., Wright W.E., Fornace A.J. Jr., Al-Qahtani M., Shay J.W.
Exome sequencing of normal and isogenic transformed human colonic epithelial cells (HCECs) reveals novel genes potentially involved in the early stages of colorectal tumorigenesis.
BMC Genomics 16 Suppl. 1:S8-S8(2015)

PubMed=27047802; DOI=10.3389/fcimb.2016.00034
Graillot V., Dormoy I., Dupuy J., Shay J.W., Huc L., Mirey G., Vignard J.
Genotoxicity of cytolethal distending toxin (CDT) on isogenic human colorectal cell lines: potential promoting effects for colorectal carcinogenesis.
Front. Cell. Infect. Microbiol. 6:34.1-34.13(2016)

Cross-references
Ontologies EFO; EFO_0009500
Other Wikidata; Q54881860
Entry history
Entry creation02-May-2016
Last entry updated24-May-2019
Version number6