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Cellosaurus HCEC 2CT (CVCL_AQ47)

[Text version]
Cell line name HCEC 2CT
Synonyms Human Colonic Epithelial Cells 2 transduced with CDK4 and Telomerase; 2CT
Accession CVCL_AQ47
Resource Identification Initiative To cite this cell line use: HCEC 2CT (RRID:CVCL_AQ47)
Comments Transfected with: HGNC; 1773; CDK4.
Transfected with: HGNC; 11730; TERT.
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Cell type: Epithelial cell of colon; CL=CL_0011108.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 52Y
Category Telomerase immortalized cell line
Publications

PubMed=19962984; DOI=10.1053/j.gastro.2009.11.052
Roig A.I., Eskiocak U., Hight S.K., Kim S.B., Delgado O., Souza R.F., Spechler S.J., Wright W.E., Shay J.W.
Immortalized epithelial cells derived from human colon biopsies express stem cell markers and differentiate in vitro.
Gastroenterology 138:1012-1021(2010)

PubMed=21527559; DOI=10.1158/0008-5472.CAN-11-0794
Eskiocak U., Kim S.B., Ly P., Roig A.I., Biglione S., Komurov K., Cornelius C., Wright W.E., White M.A., Shay J.W.
Functional parsing of driver mutations in the colorectal cancer genome reveals numerous suppressors of anchorage-independent growth.
Cancer Res. 71:4359-4365(2011)

Cross-references
Encyclopedic resources Wikidata; Q54881865
Experimental variables resources EFO; EFO_0009499
Entry history
Entry creation02-May-2016
Last entry update29-Jun-2023
Version number6