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Cellosaurus TKE2 (CVCL_AR53)

[Text version]
Cell line name TKE2
Accession CVCL_AR53
Resource Identification Initiative To cite this cell line use: TKE2 (RRID:CVCL_AR53)
Comments Characteristics: Progenitor cell isolated from the basal layer of the limbal epithelium.
Characteristics: Has applications in the cell biology of corneal epithelial cells, toxicity, and differentiation (ECACC=11033107).
Characteristics: Can be induced to differentiate into stratified epithelium on increasing the calcium concentration and addition of FBS (ECACC=11033107).
Doubling time: 34.2 hours (PubMed=18318692).
Derived from site: In situ; Eye, cornea, epithelium; UBERON=UBERON_0001772.
Cell type: Epithelial cell of cornea; CL=CL_0000575.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: CD-1.
Sex of cell Female
Category Spontaneously immortalized cell line
Publications

PubMed=18318692; DOI=10.1111/j.1582-4934.2008.00297.x
Kawakita T., Shimmura S., Hornia A., Higa K., Tseng S.C.G.
Stratified epithelial sheets engineered from a single adult murine corneal/limbal progenitor cell.
J. Cell. Mol. Med. 12:1303-1316(2008)

PubMed=19593795; DOI=10.1002/stem.174
Wang H., Tao T., Tang J., Mao Y.-H., Li W., Peng J., Tan G., Zhou Y.-P., Zhong J.-X., Tseng S.C.G., Kawakita T., Zhao Y.-X., Liu Z.-G.
Importin 13 serves as a potential marker for corneal epithelial progenitor cells.
Stem Cells 27:2516-2526(2009)

Cross-references
Cell line collections (Providers) ECACC; 11033107
Encyclopedic resources Wikidata; Q54972590
Entry history
Entry creation02-May-2016
Last entry update29-Jun-2023
Version number5