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Cellosaurus BT-474 EEI (CVCL_AR96)

[Text version]

Cell line name BT-474 EEI
Synonyms BT474-EEI; BT474 EEI; BT-474 Exogenous Estrogen Independent
Accession CVCL_AR96
Resource Identification Initiative To cite this cell line use: BT-474 EEI (RRID:CVCL_AR96)
Sequence variations Heterozygous for MAPK1 p.His61Gln (c.183C>G) (from parent cell line).
Heterozygous for PIK3CA p.Lys111Asn (c.333G>C) (ClinVar=VCV000376483) (from parent cell line).
Homozygous for TP53 p.Glu285Lys (c.853G>A) (ClinVar=VCV000420133) (from parent cell line).
Disease Invasive ductal carcinoma, not otherwise specified (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0179 (BT-474)
Sex of cell Female
Age at sampling 60Y
Category Cancer cell line

PubMed=19010901; DOI=10.1158/0008-5472.CAN-08-1776
Lewis Phillips G.D., Li G., Dugger D.L., Crocker L.M., Parsons K.L., Mai E., Blattler W.A., Lambert J.M., Chari R.V.J., Lutz R.J., Wong W.L.T., Jacobson F.S., Koeppen H., Schwall R.H., Kenkare-Mitra S.R., Spencer S.D., Sliwkowski M.X.
Targeting HER2-positive breast cancer with trastuzumab-DM1, an antibody-cytotoxic drug conjugate.
Cancer Res. 68:9280-9290(2008)

Other Wikidata; Q54798463
Entry history
Entry creation02-May-2016
Last entry update02-Jul-2020
Version number7