ID   MCF-7/S9
AC   CVCL_AS09
SY   MCF7/S9; MCF-7 subline 9
DR   cancercelllines; CVCL_AS09
DR   CancerTools; 152602
DR   Wikidata; Q54904380
DR   Ximbio; 152602
RX   PubMed=3513694;
RX   PubMed=12732292;
CC   Group: Serum/protein free medium cell line.
CC   Population: Caucasian.
CC   Doubling time: ~44 hours, 34 hours (Note=When estradiol added in medium) (PubMed=12732292).
CC   Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C4194; Invasive breast carcinoma of no special type
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0031 ! MCF-7
SX   Female
AG   69Y
CA   Cancer cell line
DT   Created: 02-05-16; Last updated: 05-10-23; Version: 15
//
RX   PubMed=3513694;
RA   Briand P., Lykkesfeldt A.E.;
RT   "Long-term cultivation of a human breast cancer cell line, MCF-7, in a
RT   chemically defined medium. Effect of estradiol.";
RL   Anticancer Res. 6:85-90(1986).
//
RX   PubMed=12732292; DOI=10.1016/S0960-0760(03)00068-2;
RA   Jensen J., Kitlen J.W., Briand P., Labrie F., Lykkesfeldt A.E.;
RT   "Effect of antiestrogens and aromatase inhibitor on basal growth of
RT   the human breast cancer cell line MCF-7 in serum-free medium.";
RL   J. Steroid Biochem. Mol. Biol. 84:469-478(2003).
//