Home  |  Contact

Cellosaurus COLO 720E contaminated (CVCL_AV69)

[Text version]

Cell line name COLO 720E contaminated
Accession CVCL_AV69
Resource Identification Initiative To cite this cell line use: COLO 720E contaminated (RRID:CVCL_AV69)
Comments Problematic cell line: Contaminated. The stock of COLO 720E distributed by ECACC was contaminated by COLO 704 (PubMed=25230021; PubMed=25877200).
Part of: OCCP ovarian cancer cell line panel.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00438.
Population: Caucasian.
Omics: Transcriptome analysis.
Sequence variations Mutation; HGNC; 9588; PTEN; Simple; p.Arg130Ter (c.388C>T); ClinVar=VCV000007819; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; 11998; TP53; Simple; p.Lys382Asnfs*40 (c.1146delA); Zygosity=Heterozygous (from parent cell line).
Disease High grade ovarian serous adenocarcinoma (NCIt: C105555)
Derived from metastatic site: Ascites from colon metastasis.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1994 (COLO 704)
Sex of cell Female
Age at sampling 46Y
Category Cancer cell line
STR profile Source(s): PubMed=25230021; PubMed=25877200

Markers:
AmelogeninX
CSF1PO10,12
D3S135817
D5S81812,15
D7S82011,13
D8S117911,12
D13S3179,12
D16S53912,13,14
D18S5114
D21S1127,31.2
FGA20,23
Penta D10.4,12 (PubMed=25230021)
11,12 (PubMed=25877200)
Penta E11,12
TH017,9.3
TPOX8
vWA15,16

Run an STR similarity search on this cell line
Web pages http://iclac.org/wp-content/uploads/Cross-Contaminations_v10_distribution.xlsx
Publications

PubMed=25230021; DOI=10.1371/journal.pone.0103988
Beaufort C.M., Helmijr J.C.A., Piskorz A.M., Hoogstraat M., Ruigrok-Ritstier K., Besselink N., Murtaza M., van IJcken W.F.J., Heine A.A.J., Smid M., Koudijs M.J., Brenton J.D., Berns E.M.J.J., Helleman J.
Ovarian cancer cell line panel (OCCP): clinical importance of in vitro morphological subtypes.
PLoS ONE 9:E103988-E103988(2014)

PubMed=25877200; DOI=10.1038/nature14397
Yu M., Selvaraj S.K., Liang-Chu M.M.Y., Aghajani S., Busse M., Yuan J., Lee G., Peale F., Klijn C., Bourgon R., Kaminker J.S., Neve R.M.
A resource for cell line authentication, annotation and quality control.
Nature 520:307-311(2015)

Cross-references
Cell line collections ECACC; 93072111 - Discontinued
Biological sample resources BioSample; SAMN03473075
Gene expression databases ArrayExpress; E-MTAB-783
GEO; GSM1291132
Other Wikidata; Q54814142
Entry history
Entry creation02-May-2016
Last entry update20-May-2021
Version number13