Cellosaurus cell line MeWo ETO 1 (CVCL_AZ62)

• Gene deletion; HGNC; 1788; CDKN2B; Zygosity=Homozygous (from parent cell line).
  
• Mutation; HGNC; 1787; CDKN2A; Simple; p.Arg80Ter (c.237_238CC>TT) (c.237_238delinsTT) (p.Pro94Leu, c.280_281CC>TT); Zygosity=Homozygous (from parent cell line).
  
• Mutation; HGNC; 6877; MAPK3; Simple; p.Pro246Ser (c.736C>T); Zygosity=Heterozygous (from parent cell line).
  
• Mutation; HGNC; 11998; TP53; Simple; p.Gln317Ter (c.949C>T); ClinVar=VCV000450344; Zygosity=Unspecified (from parent cell line).
  

PubMed=11001322; DOI=10.1002/1522-2683(20000801)21:14<3048::AID-ELPS3048>3.0.CO;2-W
Sinha P., Kohl S., Fischer J., Hutter G., Kern M., Kottgen E., Dietel M., Lage H., Schnolzer M., Schadendorf D.
Identification of novel proteins associated with the development of chemoresistance in malignant melanoma using two-dimensional electrophoresis.
Electrophoresis 21:3048-3057(2000)

PubMed=11058868; DOI=10.1002/1097-0215(20001115)88:4<535::AID-IJC4>3.0.CO;2-V
Grottke C., Mantwill K., Dietel M., Schadendorf D., Lage H.
Identification of differentially expressed genes in human melanoma cells with acquired resistance to various antineoplastic drugs.
Int. J. Cancer 88:535-546(2000)

PubMed=21475863; DOI=10.3892/mmr_00000134
Surowiak P., Drag M., Materna V., Dietel M., Lage H.
Betulinic acid exhibits stronger cytotoxic activity on the normal melanocyte NHEM-neo cell line than on drug-resistant and drug-sensitive MeWo melanoma cell lines.
Mol. Med. Rep. 2:543-548(2009)