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Cellosaurus MeWo VIN 5 (CVCL_AZ77)

[Text version]

Cell line name MeWo VIN 5
Synonyms MeWo VIN 5.0; MeWo VIN; MeWo-vindesine 5
Accession CVCL_AZ77
Resource Identification Initiative To cite this cell line use: MeWo VIN 5 (RRID:CVCL_AZ77)
Comments Selected for resistance to: ChEBI; CHEBI:36373; Vindesine.
Omics: Proteome analysis by 2D-DE.
Sequence variations Homozygous for CDKN2A p.Arg80Ter (c.237_238delinsTT) (from parent cell line).
Heterozygous for MAPK3 p.Pro246Ser (c.736C>T) (from parent cell line).
TP53 p.Gln317Ter (c.949C>T) (from parent cell line).
Disease Cutaneous melanoma (NCIt: C3510)
Derived from metastatic site: Lymph node.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0445 (MeWo)
Sex of cell Male
Age at sampling 78Y
Category Cancer cell line

PubMed=11001322; DOI=10.1002/1522-2683(20000801)21:14<3048::AID-ELPS3048>3.0.CO;2-W
Sinha P., Kohl S., Fischer J., Hutter G., Kern M., Kottgen E., Dietel M., Lage H., Schnolzer M., Schadendorf D.
Identification of novel proteins associated with the development of chemoresistance in malignant melanoma using two-dimensional electrophoresis.
Electrophoresis 21:3048-3057(2000)

PubMed=11058868; DOI=10.1002/1097-0215(20001115)88:4<535::AID-IJC4>3.0.CO;2-V
Grottke C., Mantwill K., Dietel M., Schadendorf D., Lage H.
Identification of differentially expressed genes in human melanoma cells with acquired resistance to various antineoplastic drugs.
Int. J. Cancer 88:535-546(2000)

PubMed=21475863; DOI=10.3892/mmr_00000134
Surowiak P., Drag M., Materna V., Dietel M., Lage H.
Betulinic acid exhibits stronger cytotoxic activity on the normal melanocyte NHEM-neo cell line than on drug-resistant and drug-sensitive MeWo melanoma cell lines.
Mol. Med. Rep. 2:543-548(2009)

Other Wikidata; Q54905346
Entry history
Entry creation02-May-2016
Last entry updated25-Feb-2019
Version number5