ID   H69/VDS
AC   CVCL_AZ78
DR   cancercelllines; CVCL_AZ78
DR   Wikidata; Q38568625
RX   PubMed=8391305;
CC   Population: Caucasian.
CC   Selected for resistance to: ChEBI; CHEBI:36373; Vindesine.
CC   Sequence variation: Mutation; HGNC; 8975; PIK3CA; Simple; p.Gly106_Arg108del (c.317_325delGGCAACCGT); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 9884; RB1; Simple; p.Glu748Ter (c.2242G>T); ClinVar=VCV000013078; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Glu171Ter (c.511G>T); ClinVar=VCV000634771; Zygosity=Homozygous (from parent cell line).
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C4917; Lung small cell carcinoma
DI   ORDO; Orphanet_70573; Small cell lung cancer
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1579 ! NCI-H69
SX   Male
AG   55Y
CA   Cancer cell line
DT   Created: 02-05-16; Last updated: 05-10-23; Version: 13
//
RX   PubMed=8391305; DOI=10.1038/bjc.1993.289;
RA   Ohta S., Nishio K., Kubo S., Nishio M., Ohmori T., Takahashi T.,
RA   Saijo N.;
RT   "Characterisation of a vindesine-resistant human small-cell lung
RT   cancer cell line.";
RL   Br. J. Cancer 68:74-79(1993).
//