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Cellosaurus Z-138 (CVCL_B077)

[Text version]

Cell line name Z-138
Synonyms Z138
Accession CVCL_B077
Resource Identification Initiative To cite this cell line use: Z-138 (RRID:CVCL_B077)
Comments Part of: Lymphoma Research Foundation Mantle Cell Lymphoma cell bank (LRF MCL cell bank).
Doubling time: 24 hours (PubMed=25315077).
Omics: Array-based CGH.
Omics: Deep RNAseq analysis.
Omics: Transcriptome analysis.
Miscellaneous: HLA*C loci for PubMed=24362935 was incorrect, modified version submitted by Pellat-Deceunynck C.
Derived from sampling site: Bone marrow.
Sequence variations TRAF2 p.Trp114Ter (c.341G>A) (PubMed=24362935).
HLA typing Source: PubMed=25960936
Class I
HLA-AA*01:01,23:01
HLA-BB*08:01,44:05
HLA-CC*02:02,07:06
Class II
HLA-DQDQA1*05:01,01:01
DQB1*05:01,02:01
HLA-DRDRB1*03:01,01:01

Source: PubMed=25688540
Class I
HLA-AA*01,23
HLA-BB*08,44
HLA-CC*02,07
Disease Mantle cell lymphoma (NCIt: C4337)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 70Y
Category Cancer cell line
STR profile Source(s): ATCC; PubMed=25877200

Markers:
AmelogeninX,Y
CSF1PO10,11
D3S135816
D5S81811,13
D7S8208
D8S11798,13
D13S3179,12
D16S53911
D18S5114,18
D21S1130,32.2
FGA20,22
Penta D13,15
Penta E7,18
TH016
TPOX8
vWA15,18

Run an STR similarity search on this cell line
Publications

PubMed=9669839; DOI=10.1016/S0145-2126(97)00191-4
Estrov Z., Talpaz M., Ku S., Harris D., Van Q., Beran M., Hirsch-Ginsberg C., Huh Y., Yee G., Kurzrock R.
Z-138: a new mature B-cell acute lymphoblastic leukemia cell line from a patient with transformed chronic lymphocytic leukemia.
Leuk. Res. 22:341-353(1998)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

PubMed=16183118; DOI=10.1016/j.leukres.2005.08.016
Tucker C.A., Bebb G., Klasa R.J., Chhanabhai M., Lestou V.S., Horsman D.E., Gascoyne R.D., Wiestner A., Masin D., Bally M., Williams M.E.
Four human t(11;14)(q13;q32)-containing cell lines having classic and variant features of mantle cell lymphoma.
Leuk. Res. 30:449-457(2006)

PubMed=16203034; DOI=10.1016/j.leukres.2005.08.026
Medeiros L.J., Estrov Z., Rassidakis G.Z.
Z-138 cell line was derived from a patient with blastoid variant mantle cell lymphoma.
Leuk. Res. 30:497-501(2006)

PubMed=16960149; DOI=10.1182/blood-2006-06-026500
Mestre-Escorihuela C., Rubio-Moscardo F., Richter J.A., Siebert R., Climent J., Fresquet V., Beltran E., Agirre X., Marugan I., Marin M., Rosenwald A., Sugimoto K.-J., Wheat L.M., Karran E.L., Garcia J.F., Sanchez L., Prosper F., Staudt L.M., Pinkel D., Dyer M.J.S., Martinez-Climent J.A.
Homozygous deletions localize novel tumor suppressor genes in B-cell lymphomas.
Blood 109:271-280(2007)

PubMed=24362935; DOI=10.1038/nm.3435
Rahal R., Frick M., Romero R., Korn J.M., Kridel R., Chan F.C., Meissner B., Bhang H.-E., Ruddy D., Kauffmann A., Farsidjani A., Derti A., Rakiec D., Naylor T., Pfister E., Kovats S., Kim S., Dietze K., Dorken B., Steidl C., Tzankov A., Hummel M., Monahan J., Morrissey M.P., Fritsch C., Sellers W.R., Cooke V.G., Gascoyne R.D., Lenz G., Stegmeier F.
Pharmacological and genomic profiling identifies NF-kappaB-targeted treatment strategies for mantle cell lymphoma.
Nat. Med. 20:87-92(2014)

PubMed=25960936; DOI=10.4161/21624011.2014.954893
Boegel S., Lower M., Bukur T., Sahin U., Castle J.C.
A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines.
OncoImmunology 3:E954893-E954893(2014)

PubMed=25315077; DOI=10.3109/10428194.2014.970548
Fogli L.K., Williams M.E., Connors J.M., Reid Y.A., Brown K., O'Connor O.A.
Development and characterization of a Mantle Cell Lymphoma Cell Bank in the American Type Culture Collection.
Leuk. Lymphoma 56:2114-2122(2015)

PubMed=25688540; DOI=10.1002/cyto.a.22643
Maiga S., Brosseau C., Descamps G., Dousset C., Gomez-Bougie P., Chiron D., Menoret E., Kervoelen C., Vie H., Cesbron A., Moreau-Aubry A., Amiot M., Pellat-Deceunynck C.
A simple flow cytometry-based barcode for routine authentication of multiple myeloma and mantle cell lymphoma cell lines.
Cytometry A 87:285-288(2015)

PubMed=27697772; DOI=10.1182/blood-2016-06-720490
Chiron D., Bellanger C., Papin A., Tessoulin B., Dousset C., Maiga S., Moreau A., Esbelin J., Trichet V., Chen-Kiang S., Moreau P., Touzeau C., Le Gouill S., Amiot M., Pellat-Deceunynck C.
Rational targeted therapies to overcome microenvironment-dependent expansion of mantle cell lymphoma.
Blood 128:2808-2818(2016)

Cross-references
Cell line collections ATCC; CRL-3001
Cell line databases/resources Lonza; 1605
Ontologies EFO; EFO_0005479
Biological sample resources BioSample; SAMN03471023
Gene expression databases GEO; GSM115807
GEO; GSM1044974
GEO; GSM1044975
GEO; GSM1044976
GEO; GSM1044977
GEO; GSM1266779
GEO; GSM1266780
GEO; GSM1266787
GEO; GSM1266788
GEO; GSM1266789
GEO; GSM1266790
GEO; GSM1266791
GEO; GSM1266792
GEO; GSM2322624
Other Wikidata; Q54995848
Polymorphism and mutation databases Cosmic; 2078183
Cosmic; 2088021
Cosmic; 2296992
Entry history
Entry creation06-Jun-2012
Last entry updated05-Jul-2019
Version number19