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Cellosaurus HepG2.A64 (CVCL_B0UH)

[Text version]

Cell line name HepG2.A64
Accession CVCL_B0UH
Resource Identification Initiative To cite this cell line use: HepG2.A64 (RRID:CVCL_B0UH)
Comments Registration: International Depositary Authority, China Center for Type Culture Collection; CCTCC C201163.
Population: Caucasian.
Characteristics: Transfected with a plasmid pTriexHBV1.1 containing 1.1 copies of HBV DNA (GenBank: HQ638218.1) (PubMed=28382278).
Derived from sampling site: Liver.
Sequence variations Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0027 (Hep-G2)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line
Publications

PubMed=28382278; DOI=10.3389/fcimb.2017.00091
Li H., Sheng C.-Y., Wang S., Yang L., Liang Y., Huang Y., Liu H.-B., Li P., Yang C.-J., Yang X.-X., Jia L.-L., Xie J., Wang L.-G., Hao R.-Z., Du X.-Y., Xu D.-P., Zhou J.-J., Li M.-Z., Sun Y.-S., Tong Y.-G., Li Q., Qiu S.-F., Song H.-B.
Removal of integrated hepatitis B virus DNA using CRISPR-Cas9.
Front. Cell. Infect. Microbiol. 7:91.1-91.9(2017)

Entry history
Entry creation23-Sep-2021
Last entry update23-Sep-2021
Version number1