ID   HepG2.A64
DR   Wikidata; Q108820458
RX   PubMed=28382278;
CC   Registration: International Depositary Authority, China Center for Type Culture Collection; CCTCC C201163.
CC   Population: Caucasian.
CC   Characteristics: Transfected with a plasmid pTriexHBV1.1 containing 1.1 copies of HBV DNA (GenBank: HQ638218.1) (PubMed=28382278).
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Derived from sampling site: Liver.
DI   NCIt; C3728; Hepatoblastoma
DI   ORDO; Orphanet_449; Hepatoblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens
HI   CVCL_0027 ! Hep-G2
SX   Male
AG   15Y
CA   Cancer cell line
DT   Created: 23-09-21; Last updated: 16-12-21; Version: 2
RX   PubMed=28382278; DOI=10.3389/fcimb.2017.00091;
RA   Li H., Sheng C.-Y., Wang S., Yang L., Liang Y., Huang Y., Liu H.-B.,
RA   Li P., Yang C.-J., Yang X.-X., Jia L.-L., Xie J., Wang L.-G.,
RA   Hao R.-Z., Du X.-Y., Xu D.-P., Zhou J.-J., Li M.-Z., Sun Y.-S.,
RA   Tong Y.-G., Li Q., Qiu S.-F., Song H.-B.;
RT   "Removal of integrated hepatitis B virus DNA using CRISPR-Cas9.";
RL   Front. Cell. Infect. Microbiol. 7:91.1-91.9(2017).