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Cellosaurus HepG2/TC155 (CVCL_B0UI)

[Text version]

Cell line name HepG2/TC155
Accession CVCL_B0UI
Resource Identification Initiative To cite this cell line use: HepG2/TC155 (RRID:CVCL_B0UI)
Comments Group: Patented cell line.
Registration: International Depositary Authority, China Center for Type Culture Collection; CCTCC C2013191.
Population: Caucasian.
Characteristics: Transfected with a hepatitis B virus capsid protein that contains a tetracysteine (TC) C-C-P-G-C-C insertion in position 115. The TC tag specifically reacts with a membrane-permeable biarsenical fluorescent dye (ReAsH) (PubMed=24373334).
Transfected with: UniProtKB; P03146; Hepatitis B virus genotype D subtype ayw capsid protein.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Derived from sampling site: Liver.
Sequence variations Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0027 (Hep-G2)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line
Publications

PubMed=24373334; DOI=10.1111/liv.12419
Sun S.-Z., Yan J.-J., Xia C., Lin Y.-Y., Jiang X.-R., Liu H.-J., Ren H.-P., Yan J.-W., Lin J.-S., He X.-X.
Visualizing hepatitis B virus with biarsenical labelling in living cells.
Liver Int. 34:1532-1542(2014)

Patent=CN103667194B
Lin J.-S., Liao J.-Z., Sun S.-Z., Yan J.-J., He X.-X., Chang Y., Tian D., Zhao Q., Dan Z.-L.
Human liver cancer cell line for observing life period of hepatitis B virus in cells and applications thereof.
Patent number CN103667194B, 30-Sep-2015

Cross-references
Cell line databases/resources CCRID; 4201PAT-CCTCC00437
Entry history
Entry creation23-Sep-2021
Last entry update23-Sep-2021
Version number1