ID   HepG2/TC155
DR   CCRID; 4201PAT-CCTCC00437
DR   Wikidata; Q108820460
RX   Patent=CN103667194B;
RX   PubMed=24373334;
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, China Center for Type Culture Collection; CCTCC C2013191.
CC   Population: Caucasian.
CC   Characteristics: Transfected with a hepatitis B virus capsid protein that contains a tetracysteine (TC) C-C-P-G-C-C insertion in position 115. The TC tag specifically reacts with a membrane-permeable biarsenical fluorescent dye (ReAsH) (PubMed=24373334).
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Transfected with: UniProtKB; P03146; Hepatitis B virus genotype D subtype ayw capsid protein.
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from sampling site: Liver.
DI   NCIt; C3728; Hepatoblastoma
DI   ORDO; Orphanet_449; Hepatoblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens
HI   CVCL_0027 ! Hep-G2
SX   Male
AG   15Y
CA   Cancer cell line
DT   Created: 23-09-21; Last updated: 16-12-21; Version: 2
RX   Patent=CN103667194B;
RA   Lin J.-S., Liao J.-Z., Sun S.-Z., Yan J.-J., He X.-X., Chang Y.,
RA   Tian D., Zhao Q., Dan Z.-L.;
RT   "Human liver cancer cell line for observing life period of hepatitis B
RT   virus in cells and applications thereof.";
RL   Patent number CN103667194B, 30-Sep-2015.
RX   PubMed=24373334; DOI=10.1111/liv.12419;
RA   Sun S.-Z., Yan J.-J., Xia C., Lin Y.-Y., Jiang X.-R., Liu H.-J.,
RA   Ren H.-P., Yan J.-W., Lin J.-S., He X.-X.;
RT   "Visualizing hepatitis B virus with biarsenical labelling in living
RT   cells.";
RL   Liver Int. 34:1532-1542(2014).