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Cellosaurus HUES 1 (CVCL_B139)

[Text version]

Cell line name HUES 1
Synonyms HUES-1; HUES1; HuES1; Hues1; HVRDe001-A
Accession CVCL_B139
Resource Identification Initiative To cite this cell line use: HUES 1 (RRID:CVCL_B139)
Comments From: Harvard University; Boston; USA.
Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-10-0014.
Registration: Swiss research registry; BAG-hES-IMP-0035.
Registration: UK Stem Cell Bank (UKSCB); R-05-033, Steering comm. appl. SCSC04-25(1).
Doubling time: 24 hours (PubMed=14999088).
Omics: Transcriptome analysis.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Blastocyst stage
Category Embryonic stem cell
STR profile Source(s): PubMed=19200798

Markers:
AmelogeninX
CSF1PO12
D3S135815,18
D5S81811,12
D7S82010
D8S117910,12
D13S31711,12
D16S5398,12
D18S5113
D21S1128,30
FGA21,23
Penta D9,12
Penta E7,10
TH017,9
TPOX8,9
vWA17,18

Run an STR similarity search on this cell line
Web pages https://grants.nih.gov/stem_cells/registry/current.htm?id=32
Publications

PubMed=14999088; DOI=10.1056/NEJMsr040330
Cowan C.A., Klimanskaya I., McMahon J., Atienza J., Witmyer J., Zucker J.P., Wang S., Morton C.C., McMahon A.P., Powers D., Melton D.A.
Derivation of embryonic stem-cell lines from human blastocysts.
N. Engl. J. Med. 350:1353-1356(2004)

PubMed=17572666; DOI=10.1038/nbt1318
Adewumi O., Aflatoonian B., Ahrlund-Richter L., Amit M., Andrews P.W., Beighton G., Bello P.A., Benvenisty N., Berry L.S., Bevan S., Blum B., Brooking J., Chen K.G., Choo A.B.H., Churchill G.A., Corbel M., Damjanov I., Draper J.S., Dvorak P., Emanuelsson K., Fleck R.A., Ford A., Gertow K., Gertsenstein M., Gokhale P.J., Hamilton R.S., Hampl A., Healy L.E., Hovatta O., Hyllner J., Imreh M.P., Itskovitz-Eldor J., Jackson J., Johnson J.L., Jones M., Kee K., King B.L., Knowles B.B., Lako M., Lebrin F., Mallon B.S., Manning D., Mayshar Y., McKay R.D.G., Michalska A.E., Mikkola M., Mileikovsky M., Minger S.L., Moore H.D., Mummery C.L., Nagy A., Nakatsuji N., O'Brien C.M., Oh S.K.W., Olsson C., Otonkoski T., Park K.-Y., Passier R., Patel H., Patel M., Pedersen R., Pera M.F., Piekarczyk M.S., Pera R.A.R., Reubinoff B.E., Robins A.J., Rossant J., Rugg-Gunn P., Schulz T.C., Semb H., Sherrer E.S., Siemen H., Stacey G.N., Stojkovic M., Suemori H., Szatkiewicz J., Turetsky T., Tuuri T., van den Brink S., Vintersten K., Vuoristo S., Ward D., Weaver T.A., Young L.A., Zhang W.
Characterization of human embryonic stem cell lines by the International Stem Cell Initiative.
Nat. Biotechnol. 25:803-816(2007)

PubMed=19200798; DOI=10.1016/j.stem.2008.12.001
Chen A.E., Egli D., Niakan K.K., Deng J., Akutsu H., Yamaki M., Cowan C., Fitz-Gerald C., Zhang K., Melton D.A., Eggan K.
Optimal timing of inner cell mass isolation increases the efficiency of human embryonic stem cell derivation and allows generation of sibling cell lines.
Cell Stem Cell 4:103-106(2009)

PubMed=21295703; DOI=10.1016/j.cell.2010.12.032
Bock C., Kiskinis E., Verstappen G., Gu H., Boulting G., Smith Z.D., Ziller M., Croft G.F., Amoroso M.W., Oakley D.H., Gnirke A., Eggan K., Meissner A.
Reference maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines.
Cell 144:439-452(2011)

PubMed=21714037; DOI=10.1002/stem.681
Ramirez J.-M., Gerbal-Chaloin S., Milhavet O., Qiang B., Becker F., Assou S., Lemaitre J.-M., Hamamah S., De Vos J.
Brief report: benchmarking human pluripotent stem cell markers during differentiation into the three germ layers unveils a striking heterogeneity: all markers are not equal.
Stem Cells 29:1469-1474(2011)

Cross-references
Cell line databases/resources hPSCreg; HVRDe001-A
ISCR; 102
SKIP; SKIP001905
Ontologies EFO; EFO_0005355
Biological sample resources eagle-i; harvard.eagle-i.net/i/00000140-2baf-4e23-a870-ad6980000000
ENCODE; ENCBS771TSF
ENCODE; ENCBS790PAZ
ENCODE; ENCBS836MPJ
Gene expression databases GEO; GSM637758
Other Wikidata; Q54896736
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2019
Version number19