ID   HUES 3
AC   CVCL_B161
SY   HUES-3; HuES-3; HUES3; HuES3; Hues3; HVRDe003-A
DR   CLO; CLO_0037316
DR   EFO; EFO_0007080
DR   eagle-i; harvard.eagle-i.net/i/00000140-2fd4-40c4-a870-ad6980000000
DR   ENCODE; ENCBS087WPL
DR   ENCODE; ENCBS433HCT
DR   GEO; GSM608011
DR   GEO; GSM608029
DR   GEO; GSM621767
DR   GEO; GSM637759
DR   GEO; GSM670075
DR   hPSCreg; HVRDe003-A
DR   ISCR; 104
DR   SKIP; SKIP001481
DR   SKIP; SKIP001907
DR   Wikidata; Q54896761
RX   PubMed=14999088;
RX   PubMed=17572666;
RX   PubMed=19200798;
RX   PubMed=20973834;
RX   PubMed=21295703;
RX   PubMed=21637780;
RX   PubMed=22514597;
WW   https://grants.nih.gov/stem_cells/registry/current.htm?id=34
CC   From: Harvard University; Boston; USA.
CC   Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-10-0016.
CC   Registration: Swiss research registry; BAG-hES-IMP-0036.
CC   Registration: UK Stem Cell Bank (UKSCB); R-05-034, Steering comm. appl. SCSC04-25(3).
CC   Doubling time: 60 hours (PubMed=14999088).
CC   Omics: DNA methylation analysis.
CC   Omics: Transcriptome analysis.
ST   Source(s): PubMed=19200798; PubMed=20973834; PubMed=21637780
ST   Amelogenin: X,Y
ST   CSF1PO: 11,12
ST   D13S317: 8,14
ST   D16S539: 12,14
ST   D18S51: 13,17
ST   D21S11: 28,29
ST   D3S1358: 15,16
ST   D5S818: 12
ST   D7S820: 8,11
ST   D8S1179: 12,13
ST   FGA: 22,24
ST   Penta D: 9,12
ST   Penta E: 11,12
ST   TH01: 7,8
ST   TPOX: 8,11
ST   vWA: 16,17
OX   NCBI_TaxID=9606; ! Homo sapiens
SX   Male
AG   Blastocyst stage
CA   Embryonic stem cell
DT   Created: 06-06-12; Last updated: 19-12-19; Version: 19
//
RX   PubMed=14999088; DOI=10.1056/NEJMsr040330;
RA   Cowan C.A., Klimanskaya I., McMahon J., Atienza J., Witmyer J.,
RA   Zucker J.P., Wang S., Morton C.C., McMahon A.P., Powers D.,
RA   Melton D.A.;
RT   "Derivation of embryonic stem-cell lines from human blastocysts.";
RL   N. Engl. J. Med. 350:1353-1356(2004).
//
RX   PubMed=17572666; DOI=10.1038/nbt1318;
RA   Adewumi O., Aflatoonian B., Ahrlund-Richter L., Amit M., Andrews P.W.,
RA   Beighton G., Bello P.A., Benvenisty N., Berry L.S., Bevan S., Blum B.,
RA   Brooking J., Chen K.G., Choo A.B.H., Churchill G.A., Corbel M.,
RA   Damjanov I., Draper J.S., Dvorak P., Emanuelsson K., Fleck R.A.,
RA   Ford A., Gertow K., Gertsenstein M., Gokhale P.J., Hamilton R.S.,
RA   Hampl A., Healy L.E., Hovatta O., Hyllner J., Imreh M.P.,
RA   Itskovitz-Eldor J., Jackson J., Johnson J.L., Jones M., Kee K.,
RA   King B.L., Knowles B.B., Lako M., Lebrin F., Mallon B.S., Manning D.,
RA   Mayshar Y., McKay R.D.G., Michalska A.E., Mikkola M., Mileikovsky M.,
RA   Minger S.L., Moore H.D., Mummery C.L., Nagy A., Nakatsuji N.,
RA   O'Brien C.M., Oh S.K.W., Olsson C., Otonkoski T., Park K.-Y.,
RA   Passier R., Patel H., Patel M., Pedersen R., Pera M.F.,
RA   Piekarczyk M.S., Pera R.A.R., Reubinoff B.E., Robins A.J., Rossant J.,
RA   Rugg-Gunn P., Schulz T.C., Semb H., Sherrer E.S., Siemen H.,
RA   Stacey G.N., Stojkovic M., Suemori H., Szatkiewicz J., Turetsky T.,
RA   Tuuri T., van den Brink S., Vintersten K., Vuoristo S., Ward D.,
RA   Weaver T.A., Young L.A., Zhang W.;
RT   "Characterization of human embryonic stem cell lines by the
RT   International Stem Cell Initiative.";
RL   Nat. Biotechnol. 25:803-816(2007).
//
RX   PubMed=19200798; DOI=10.1016/j.stem.2008.12.001;
RA   Chen A.E., Egli D., Niakan K.K., Deng J., Akutsu H., Yamaki M.,
RA   Cowan C., Fitz-Gerald C., Zhang K., Melton D.A., Eggan K.;
RT   "Optimal timing of inner cell mass isolation increases the efficiency
RT   of human embryonic stem cell derivation and allows generation of
RT   sibling cell lines.";
RL   Cell Stem Cell 4:103-106(2009).
//
RX   PubMed=20973834; DOI=10.1111/j.1749-0774.2010.00090.x;
RA   Wu R.-R., Xu C.-M., Jin F., Tan Z., Gu B., Chen L.-B., Yao X.,
RA   Zhang M.;
RT   "Derivation, characterization and differentiation of a new human
RT   embryonic stem cell line from a Chinese hatched blastocyst assisted by
RT   a non-contact laser system.";
RL   Hum. Cell 23:89-102(2010).
//
RX   PubMed=21295703; DOI=10.1016/j.cell.2010.12.032;
RA   Bock C., Kiskinis E., Verstappen G., Gu H., Boulting G., Smith Z.D.,
RA   Ziller M., Croft G.F., Amoroso M.W., Oakley D.H., Gnirke A., Eggan K.,
RA   Meissner A.;
RT   "Reference maps of human ES and iPS cell variation enable
RT   high-throughput characterization of pluripotent cell lines.";
RL   Cell 144:439-452(2011).
//
RX   PubMed=21637780; DOI=10.1371/journal.pgen.1002085;
RA   Nishino K., Toyoda M., Yamazaki-Inoue M., Fukawatase Y., Chikazawa E.,
RA   Sakaguchi H., Akutsu H., Umezawa A.;
RT   "DNA methylation dynamics in human induced pluripotent stem cells over
RT   time.";
RL   PLoS Genet. 7:E1002085-E1002085(2011).
//
RX   PubMed=22514597; DOI=10.1371/journal.pone.0030743;
RA   Sandt C., Feraud O., Oudrhiri N., Bonnet M.-L., Meunier M.-C.,
RA   Valogne Y., Bertrand A., Raphael M., Griscelli F., Turhan A.G.,
RA   Dumas P., Bennaceur-Griscelli A.;
RT   "Identification of spectral modifications occurring during
RT   reprogramming of somatic cells.";
RL   PLoS ONE 7:E30743-E30743(2012).
//