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Cellosaurus HUES 45 (CVCL_B178)

[Text version]
Cell line name HUES 45
Synonyms HUES45
Accession CVCL_B178
Resource Identification Initiative To cite this cell line use: HUES 45 (RRID:CVCL_B178)
Comments From: Harvard University; Boston; USA.
Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-10-0076.
Omics: Deep exome analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Blastocyst stage
Category Embryonic stem cell
STR profile Source(s): PubMed=19200798

Markers:
AmelogeninX
CSF1PO10,11
D2S133817
D3S135816,18
D5S81811
D7S8209,12
D8S117910,13
D13S31711,14
D16S53911,13
D18S5113,17
D19S43312,15.2
D21S1130,32.2
FGA20,24
TH017
TPOX8,9
vWA16,19

Run an STR similarity search on this cell line
Publications

PubMed=19200798; DOI=10.1016/j.stem.2008.12.001
Chen A.E., Egli D., Niakan K.K., Deng J., Akutsu H., Yamaki M., Cowan C.A., Fitz-Gerald C., Zhang K., Melton D.A., Eggan K.C.
Optimal timing of inner cell mass isolation increases the efficiency of human embryonic stem cell derivation and allows generation of sibling cell lines.
Cell Stem Cell 4:103-106(2009)

PubMed=21295703; DOI=10.1016/j.cell.2010.12.032
Bock C., Kiskinis E., Verstappen G., Gu H.-C., Boulting G.L., Smith Z.D., Ziller M.J., Croft G.F., Amoroso M.W., Oakley D.H., Gnirke A., Eggan K.C., Meissner A.
Reference maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines.
Cell 144:439-452(2011)

PubMed=28445466; DOI=10.1038/nature22312
Merkle F.T., Ghosh S., Kamitaki N., Mitchell J., Avior Y., Mello C., Kashin S., Mekhoubad S., Ilic D., Charlton M., Saphier G., Handsaker R.E., Genovese G., Bar S., Benvenisty N., McCarroll S.A., Eggan K.C.
Human pluripotent stem cells recurrently acquire and expand dominant negative P53 mutations.
Nature 545:229-233(2017)

Cross-references
Cell line databases/resources ISCR; 1301
NIHhESC; NIHhESC-10-0076
SKIP; SKIP001527
Biological sample resources ENCODE; ENCBS142AAM
ENCODE; ENCBS384VFC
Encyclopedic resources Wikidata; Q54896780
Experimental variables resources EFO; EFO_0007082
Gene expression databases GEO; GSM637766
GEO; GSM670084
GEO; GSM670091
Entry history
Entry creation06-Jun-2012
Last entry update05-Oct-2023
Version number22