ID   HUES 6
AC   CVCL_B194
SY   HUES-6; HUES6; HuES6; Hues6; HVRDe006-A
DR   EFO; EFO_0007086
DR   BioSamples; SAMEA7771168
DR   eagle-i; harvard.eagle-i.net/i/00000140-2fd8-19b3-a870-ad6980000000
DR   ENCODE; ENCBS153ORV
DR   ENCODE; ENCBS271TBU
DR   ENCODE; ENCBS530IZG
DR   ENCODE; ENCBS912XKA
DR   GEO; GSM525424
DR   GEO; GSM525425
DR   GEO; GSM525426
DR   GEO; GSM608012
DR   GEO; GSM621700
DR   GEO; GSM637760
DR   GEO; GSM669885
DR   GEO; GSM669886
DR   GEO; GSM669887
DR   GEO; GSM669888
DR   GEO; GSM669889
DR   GEO; GSM669890
DR   GEO; GSM669891
DR   GEO; GSM669892
DR   GEO; GSM669893
DR   GEO; GSM669894
DR   GEO; GSM669895
DR   GEO; GSM669897
DR   GEO; GSM669898
DR   GEO; GSM670080
DR   GEO; GSM1112774
DR   GEO; GSM1112776
DR   GEO; GSM1153528
DR   hPSCreg; HVRDe006-A
DR   ISCR; 107
DR   SKIP; SKIP001484
DR   SKIP; SKIP001910
DR   Wikidata; Q54896798
RX   PubMed=14999088;
RX   PubMed=17572666;
RX   PubMed=19200798;
RX   PubMed=21295703;
RX   PubMed=21637780;
RX   PubMed=28677534;
WW   https://grants.nih.gov/stem_cells/registry/current.htm?id=37
CC   From: Harvard University; Boston; USA.
CC   Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-10-0019.
CC   Registration: Swiss research registry; BAG-hES-IMP-0038.
CC   Registration: UK Stem Cell Bank (UKSCB); R-06-009, Steering comm. appl. SCSC04-25(6).
CC   Doubling time: 24 hours (PubMed=14999088).
CC   Omics: DNA methylation analysis.
CC   Omics: H3K27ac ChIP-seq epigenome analysis.
CC   Omics: H3K27me3 ChIP-seq epigenome analysis.
CC   Omics: H3K36me3 ChIP-seq epigenome analysis.
CC   Omics: H3K4me1 ChIP-seq epigenome analysis.
CC   Omics: H3K4me3 ChIP-seq epigenome analysis.
CC   Omics: H3K9ac ChIP-seq epigenome analysis.
CC   Omics: H3K9me3 ChIP-seq epigenome analysis.
CC   Omics: Transcriptome analysis.
ST   Source(s): PubMed=19200798; PubMed=21637780; PubMed=28677534
ST   Amelogenin: X
ST   CSF1PO: 11,12
ST   D12S391: 24,25
ST   D13S317: 11
ST   D16S539: 10,11
ST   D18S51: 12,14
ST   D19S433: 13,15
ST   D1S1656: 15,18.3
ST   D21S11: 30
ST   D2S1338: 23,24
ST   D3S1358: 16,18
ST   D5S818: 12
ST   D6S1043: 11,13
ST   D7S820: 8,11
ST   D8S1179: 10,13
ST   FGA: 23,24
ST   Penta D: 9,10
ST   Penta E: 12
ST   TH01: 8,9.3
ST   TPOX: 9,11
ST   vWA: 15,16
OX   NCBI_TaxID=9606; ! Homo sapiens
SX   Female
AG   Blastocyst stage
CA   Embryonic stem cell
DT   Created: 06-06-12; Last updated: 02-07-20; Version: 20
//
RX   PubMed=14999088; DOI=10.1056/NEJMsr040330;
RA   Cowan C.A., Klimanskaya I.V., McMahon J., Atienza J., Witmyer J.,
RA   Zucker J.P., Wang S., Morton C.C., McMahon A.P., Powers D.,
RA   Melton D.A.;
RT   "Derivation of embryonic stem-cell lines from human blastocysts.";
RL   N. Engl. J. Med. 350:1353-1356(2004).
//
RX   PubMed=17572666; DOI=10.1038/nbt1318;
RA   Adewumi O., Aflatoonian B., Ahrlund-Richter L., Amit M., Andrews P.W.,
RA   Beighton G., Bello P.A., Benvenisty N., Berry L.S., Bevan S., Blum B.,
RA   Brooking J., Chen K.G., Choo A.B.H., Churchill G.A., Corbel M.,
RA   Damjanov I., Draper J.S., Dvorak P., Emanuelsson K., Fleck R.A.,
RA   Ford A., Gertow K., Gertsenstein M., Gokhale P.J., Hamilton R.S.,
RA   Hampl A., Healy L.E., Hovatta O., Hyllner J., Imreh M.P.,
RA   Itskovitz-Eldor J., Jackson J., Johnson J.L., Jones M., Kee K.,
RA   King B.L., Knowles B.B., Lako M., Lebrin F., Mallon B.S., Manning D.,
RA   Mayshar Y., McKay R.D.G., Michalska A.E., Mikkola M., Mileikovsky M.,
RA   Minger S.L., Moore H.D., Mummery C.L., Nagy A., Nakatsuji N.,
RA   O'Brien C.M., Oh S.K.W., Olsson C., Otonkoski T., Park K.-Y.,
RA   Passier R., Patel H., Patel M., Pedersen R., Pera M.F.,
RA   Piekarczyk M.S., Pera R.A.R., Reubinoff B.E., Robins A.J., Rossant J.,
RA   Rugg-Gunn P., Schulz T.C., Semb H., Sherrer E.S., Siemen H.,
RA   Stacey G.N., Stojkovic M., Suemori H., Szatkiewicz J., Turetsky T.,
RA   Tuuri T., van den Brink S., Vintersten K., Vuoristo S., Ward D.,
RA   Weaver T.A., Young L.A., Zhang W.-D.;
RT   "Characterization of human embryonic stem cell lines by the
RT   International Stem Cell Initiative.";
RL   Nat. Biotechnol. 25:803-816(2007).
//
RX   PubMed=19200798; DOI=10.1016/j.stem.2008.12.001;
RA   Chen A.E., Egli D., Niakan K.K., Deng J., Akutsu H., Yamaki M.,
RA   Cowan C.A., Fitz-Gerald C., Zhang K., Melton D.A., Eggan K.C.;
RT   "Optimal timing of inner cell mass isolation increases the efficiency
RT   of human embryonic stem cell derivation and allows generation of
RT   sibling cell lines.";
RL   Cell Stem Cell 4:103-106(2009).
//
RX   PubMed=21295703; DOI=10.1016/j.cell.2010.12.032;
RA   Bock C., Kiskinis E., Verstappen G., Gu H., Boulting G.L., Smith Z.D.,
RA   Ziller M., Croft G.F., Amoroso M.W., Oakley D.H., Gnirke A., Eggan K.C.,
RA   Meissner A.;
RT   "Reference maps of human ES and iPS cell variation enable
RT   high-throughput characterization of pluripotent cell lines.";
RL   Cell 144:439-452(2011).
//
RX   PubMed=21637780; DOI=10.1371/journal.pgen.1002085;
RA   Nishino K., Toyoda M., Yamazaki-Inoue M., Fukawatase Y., Chikazawa E.,
RA   Sakaguchi H., Akutsu H., Umezawa A.;
RT   "DNA methylation dynamics in human induced pluripotent stem cells over
RT   time.";
RL   PLoS Genet. 7:E1002085-E1002085(2011).
//
RX   PubMed=28677534; DOI=10.1016/j.scr.2017.03.015;
RA   Marczenke M., Fell J., Piccini I., Ropke A., Seebohm G., Greber B.;
RT   "Generation and cardiac subtype-specific differentiation of
RT   PITX2-deficient human iPS cell lines for exploring familial atrial
RT   fibrillation.";
RL   Stem Cell Res. 21:26-28(2017).
//