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Cellosaurus HUES 7 (CVCL_B205)

Cell line name HUES 7
Synonyms HUES-7; HUES7; HuES7; HVRDe007-A
Accession CVCL_B205
Resource Identification Initiative To cite this cell line use: HUES 7 (RRID:CVCL_B205)
Comments From: Harvard University; Boston; USA.
Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-10-0020.
Registration: UK Stem Cell Bank (UKSCB); R-05-035, Steering comm. appl. SCSC04-25(7).
Doubling time: 48 hours (PubMed=14999088).
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
HLA typing Source: PubMed=16919167
Class I
HLA-AA*02:03
HLA-BB*35,51
HLA-CC*04,14
Class II
HLA-DQDQB1*03,06
HLA-DRDRB1*04,15
DRB5*01
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Blastocyst stage
Category Embryonic stem cell
STR profile Source(s): PubMed=16919167; PubMed=19200798

Markers:
AmelogeninX,Y
CSF1PO12
D3S135815,18
D5S81811,13
D7S8208,11
D8S117910,11
D13S31711,12
D16S53911,12
D18S5114,15
D21S1127,32.2
FGA25
Penta D9,11
Penta E7,13
TH016,9.3
TPOX8
vWA16,18

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Publications

PubMed=14999088; DOI=10.1056/NEJMsr040330
Cowan C.A., Klimanskaya I.V., McMahon J., Atienza J., Witmyer J., Zucker J.P., Wang S.-P., Morton C.C., McMahon A.P., Powers D., Melton D.A.
Derivation of embryonic stem-cell lines from human blastocysts.
N. Engl. J. Med. 350:1353-1356(2004)

PubMed=16919167; DOI=10.1186/1741-7007-4-28
Josephson R., Sykes G.R., Liu Y., Ording C.J., Xu W.-N., Zeng X.-M., Shin S., Loring J.F., Maitra A., Rao M.S., Auerbach J.M.
A molecular scheme for improved characterization of human embryonic stem cell lines.
BMC Biol. 4:28.1-28.13(2006)

PubMed=17287758; DOI=10.1038/nbt1285
Baker D.E.C., Harrison N.J., Maltby E., Smith K., Moore H.D., Shaw P.J., Heath P.R., Holden H., Andrews P.W.
Adaptation to culture of human embryonic stem cells and oncogenesis in vivo.
Nat. Biotechnol. 25:207-215(2007)

PubMed=17572666; DOI=10.1038/nbt1318
Adewumi O., Aflatoonian B., Ahrlund-Richter L., Amit M., Andrews P.W., Beighton G., Bello P.A., Benvenisty N., Berry L.S., Bevan S., Blum B., Brooking J., Chen K.G., Choo A.B.-H., Churchill G.A., Corbel M., Damjanov I., Draper J.S., Dvorak P., Emanuelsson K., Fleck R.A., Ford A., Gertow K., Gertsenstein M., Gokhale P.J., Hamilton R.S., Hampl A., Healy L.E., Hovatta O., Hyllner J., Imreh M.P., Itskovitz-Eldor J., Jackson J., Johnson J.L., Jones M., Kee K., King B.L., Knowles B.B., Lako M., Lebrin F., Mallon B.S., Manning D., Mayshar Y., McKay R.D.G., Michalska A.E., Mikkola M., Mileikovsky M., Minger S.L., Moore H.D., Mummery C.L., Nagy A., Nakatsuji N., O'Brien C.M., Oh S.K.-W., Olsson C., Otonkoski T., Park K.-Y., Passier R., Patel H., Patel M.J., Pedersen R., Pera M.F., Piekarczyk M.S., Reijo Pera R.A., Reubinoff B.E., Robins A.J., Rossant J., Rugg-Gunn P., Schulz T.C., Semb H., Sherrer E.S., Siemen H., Stacey G.N., Stojkovic M., Suemori H., Szatkiewicz J., Turetsky T.T., Tuuri T., van den Brink S., Vintersten K., Vuoristo S., Ward-van Oostwaard D., Weaver T.A., Young L.A., Zhang W.-D.
Characterization of human embryonic stem cell lines by the International Stem Cell Initiative.
Nat. Biotechnol. 25:803-816(2007)

PubMed=18772870; DOI=10.1038/nprot.2008.140
Braam S.R., Denning C., Matsa E., Young L.E., Passier R., Mummery C.L.
Feeder-free culture of human embryonic stem cells in conditioned medium for efficient genetic modification.
Nat. Protoc. 3:1435-1443(2008)

PubMed=19200798; DOI=10.1016/j.stem.2008.12.001
Chen A.E., Egli D., Niakan K.K., Deng J., Akutsu H., Yamaki M., Cowan C.A., Fitz-Gerald C., Zhang K., Melton D.A., Eggan K.C.
Optimal timing of inner cell mass isolation increases the efficiency of human embryonic stem cell derivation and allows generation of sibling cell lines.
Cell Stem Cell 4:103-106(2009)

Cross-references
Cell line databases/resources hPSCreg; HVRDe007-A
ISCR; 108
NIHhESC; NIHhESC-10-0020
SKIP; SKIP001485
SKIP; SKIP001911
TOKU-E; 4083
Encyclopedic resources Wikidata; Q54896812
Entry history
Entry creation06-Jun-2012
Last entry update29-Jun-2023
Version number22