ID   HUES 8
AC   CVCL_B207
SY   HUES-8; HUES8; HuES8; HVRDe008-A
DR   EFO; EFO_0007093
DR   ENCODE; ENCBS458EUG
DR   ENCODE; ENCBS989VLH
DR   GEO; GSM608013
DR   GEO; GSM608030
DR   GEO; GSM621709
DR   GEO; GSM637761
DR   hPSCreg; HVRDe008-A
DR   ISCR; 109
DR   NIHhESC; NIHhESC-10-0021
DR   SKIP; SKIP001912
DR   Wikidata; Q54896820
RX   PubMed=14999088;
RX   PubMed=17572666;
RX   PubMed=19200798;
RX   PubMed=21295703;
RX   PubMed=21637780;
CC   From: Harvard University; Boston; USA.
CC   Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-10-0021.
CC   Registration: Swiss research registry; BAG-hES-IMP-0056.
CC   Registration: UK Stem Cell Bank (UKSCB); R-06-018, Steering comm. appl. SCSC04-25(8).
CC   Doubling time: 48 hours (PubMed=14999088).
CC   Omics: DNA methylation analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
CC   Cell type: Embryonic stem cell; CL=CL_0002322.
ST   Source(s): PubMed=19200798; PubMed=21637780
ST   Amelogenin: X,Y
ST   CSF1PO: 10,12
ST   D13S317: 12,14
ST   D16S539: 9,12
ST   D18S51: 12,16
ST   D21S11: 28,29
ST   D3S1358: 15,19
ST   D5S818: 11
ST   D7S820: 11,12
ST   D8S1179: 13
ST   FGA: 20,25
ST   Penta D: 10,11
ST   Penta E: 7,10
ST   TH01: 7,9
ST   TPOX: 8,11
ST   vWA: 15,19
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   Blastocyst stage
CA   Embryonic stem cell
DT   Created: 06-06-12; Last updated: 29-06-23; Version: 22
//
RX   PubMed=14999088; DOI=10.1056/NEJMsr040330;
RA   Cowan C.A., Klimanskaya I.V., McMahon J., Atienza J., Witmyer J.,
RA   Zucker J.P., Wang S.-P., Morton C.C., McMahon A.P., Powers D.,
RA   Melton D.A.;
RT   "Derivation of embryonic stem-cell lines from human blastocysts.";
RL   N. Engl. J. Med. 350:1353-1356(2004).
//
RX   PubMed=17572666; DOI=10.1038/nbt1318;
RA   Adewumi O., Aflatoonian B., Ahrlund-Richter L., Amit M., Andrews P.W.,
RA   Beighton G., Bello P.A., Benvenisty N., Berry L.S., Bevan S., Blum B.,
RA   Brooking J., Chen K.G., Choo A.B.-H., Churchill G.A., Corbel M.,
RA   Damjanov I., Draper J.S., Dvorak P., Emanuelsson K., Fleck R.A.,
RA   Ford A., Gertow K., Gertsenstein M., Gokhale P.J., Hamilton R.S.,
RA   Hampl A., Healy L.E., Hovatta O., Hyllner J., Imreh M.P.,
RA   Itskovitz-Eldor J., Jackson J., Johnson J.L., Jones M., Kee K.,
RA   King B.L., Knowles B.B., Lako M., Lebrin F., Mallon B.S., Manning D.,
RA   Mayshar Y., McKay R.D.G., Michalska A.E., Mikkola M., Mileikovsky M.,
RA   Minger S.L., Moore H.D., Mummery C.L., Nagy A., Nakatsuji N.,
RA   O'Brien C.M., Oh S.K.-W., Olsson C., Otonkoski T., Park K.-Y.,
RA   Passier R., Patel H., Patel M.J., Pedersen R., Pera M.F.,
RA   Piekarczyk M.S., Reijo Pera R.A., Reubinoff B.E., Robins A.J.,
RA   Rossant J., Rugg-Gunn P., Schulz T.C., Semb H., Sherrer E.S., Siemen H.,
RA   Stacey G.N., Stojkovic M., Suemori H., Szatkiewicz J., Turetsky T.T.,
RA   Tuuri T., van den Brink S., Vintersten K., Vuoristo S.,
RA   Ward-van Oostwaard D., Weaver T.A., Young L.A., Zhang W.-D.;
RT   "Characterization of human embryonic stem cell lines by the
RT   International Stem Cell Initiative.";
RL   Nat. Biotechnol. 25:803-816(2007).
//
RX   PubMed=19200798; DOI=10.1016/j.stem.2008.12.001;
RA   Chen A.E., Egli D., Niakan K.K., Deng J., Akutsu H., Yamaki M.,
RA   Cowan C.A., Fitz-Gerald C., Zhang K., Melton D.A., Eggan K.C.;
RT   "Optimal timing of inner cell mass isolation increases the efficiency
RT   of human embryonic stem cell derivation and allows generation of
RT   sibling cell lines.";
RL   Cell Stem Cell 4:103-106(2009).
//
RX   PubMed=21295703; DOI=10.1016/j.cell.2010.12.032;
RA   Bock C., Kiskinis E., Verstappen G., Gu H.-C., Boulting G.L., Smith Z.D.,
RA   Ziller M.J., Croft G.F., Amoroso M.W., Oakley D.H., Gnirke A.,
RA   Eggan K.C., Meissner A.;
RT   "Reference maps of human ES and iPS cell variation enable
RT   high-throughput characterization of pluripotent cell lines.";
RL   Cell 144:439-452(2011).
//
RX   PubMed=21637780; DOI=10.1371/journal.pgen.1002085;
RA   Nishino K., Toyoda M., Yamazaki-Inoue M., Fukawatase Y., Chikazawa E.,
RA   Sakaguchi H., Akutsu H., Umezawa A.;
RT   "DNA methylation dynamics in human induced pluripotent stem cells over
RT   time.";
RL   PLoS Genet. 7:E1002085-E1002085(2011).
//