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Cellosaurus Sup-M2-TS (CVCL_B228)

[Text version]

Cell line name Sup-M2-TS
Synonyms Sup-M2TS; TS
Accession CVCL_B228
Resource Identification Initiative To cite this cell line use: Sup-M2-TS (RRID:CVCL_B228)
Comments Derived from sampling site: Cerebrospinal fluid.
Sequence variations Gene fusion; HGNC; 427; ALK + HGNC; 7910; NPM1; Name(s)=NPM1-ALK (PubMed=26657151).
Disease Anaplastic large cell lymphoma, ALK-positive (NCIt: C37193)
ALK-positive anaplastic large cell lymphoma (ORDO: Orphanet_300895)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2209 (SUP-M2)
Sex of cell Female
Age at sampling 5Y
Category Cancer cell line
Publications

PubMed=26657151; DOI=10.1038/onc.2015.456
Ceccon M., Merlo M.E.B., Mologni L., Poggio T., Varesio L.M., Menotti M., Bombelli S., Rigolio R., Manazza A.D., Di Giacomo F., Ambrogio C., Giudici G., Casati C., Mastini C., Compagno M., Turner S.D., Gambacorti-Passerini C., Chiarle R., Voena C.
Excess of NPM-ALK oncogenic signaling promotes cellular apoptosis and drug dependency.
Oncogene 35:3854-3865(2016)

Cross-references
Anatomy/cell type resources BTO; BTO:0004867
Encyclopedic resources Wikidata; Q54970879
Gene expression databases GEO; GSM1217149
Polymorphism and mutation databases Progenetix; CVCL_B228
Entry history
Entry creation06-Jun-2012
Last entry update20-May-2021
Version number13