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Cellosaurus KhES-1 (CVCL_B231)

[Text version]

Cell line name KhES-1
Synonyms KHES-1; KhES1; KUIMSe001-A
Accession CVCL_B231
Resource Identification Initiative To cite this cell line use: KhES-1 (RRID:CVCL_B231)
Comments From: Institute for Frontier Medical Sciences, Kyoto University; Kyoto; Japan.
Registration: NIH Human Embryonic Stem Cell Registry; pending review.
Omics: DNA methylation analysis.
Omics: Transcriptome analysis.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_T924 (KhES-1 CAG-EGFP )CVCL_T917 (KhES-1 subline 1 )CVCL_T918 (KhES-1 subline 2 )
CVCL_T919 (KhES-1 subline 3 )
Sex of cell Female
Age at sampling Blastocyst stage
Category Embryonic stem cell
Web pages https://grants.nih.gov/stem_cells/registry/pending.htm
http://www.nbrp.jp/report/reportProjectEn.jsp?project=esCell
Publications

PubMed=17572666; DOI=10.1038/nbt1318
Adewumi O., Aflatoonian B., Ahrlund-Richter L., Amit M., Andrews P.W., Beighton G., Bello P.A., Benvenisty N., Berry L.S., Bevan S., Blum B., Brooking J., Chen K.G., Choo A.B.H., Churchill G.A., Corbel M., Damjanov I., Draper J.S., Dvorak P., Emanuelsson K., Fleck R.A., Ford A., Gertow K., Gertsenstein M., Gokhale P.J., Hamilton R.S., Hampl A., Healy L.E., Hovatta O., Hyllner J., Imreh M.P., Itskovitz-Eldor J., Jackson J., Johnson J.L., Jones M., Kee K., King B.L., Knowles B.B., Lako M., Lebrin F., Mallon B.S., Manning D., Mayshar Y., McKay R.D.G., Michalska A.E., Mikkola M., Mileikovsky M., Minger S.L., Moore H.D., Mummery C.L., Nagy A., Nakatsuji N., O'Brien C.M., Oh S.K.W., Olsson C., Otonkoski T., Park K.-Y., Passier R., Patel H., Patel M., Pedersen R., Pera M.F., Piekarczyk M.S., Pera R.A.R., Reubinoff B.E., Robins A.J., Rossant J., Rugg-Gunn P., Schulz T.C., Semb H., Sherrer E.S., Siemen H., Stacey G.N., Stojkovic M., Suemori H., Szatkiewicz J., Turetsky T., Tuuri T., van den Brink S., Vintersten K., Vuoristo S., Ward D., Weaver T.A., Young L.A., Zhang W.-D.
Characterization of human embryonic stem cell lines by the International Stem Cell Initiative.
Nat. Biotechnol. 25:803-816(2007)

PubMed=21460823; DOI=10.1038/nmeth.1591
Okita K., Matsumura Y., Sato Y., Okada A., Morizane A., Okamoto S., Hong H., Nakagawa M., Tanabe K., Tezuka K., Shibata T., Kunisada T., Takahashi M., Takahashi J., Saji H., Yamanaka S.
A more efficient method to generate integration-free human iPS cells.
Nat. Methods 8:409-412(2011)

PubMed=22802639; DOI=10.1073/pnas.1209979109
Kajiwara M., Aoi T., Okita K., Takahashi R., Inoue H., Takayama N., Endo H., Eto K., Toguchida J., Uemoto S., Yamanaka S.
Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells.
Proc. Natl. Acad. Sci. U.S.A. 109:12538-12543(2012)

PubMed=24259714; DOI=10.1073/pnas.1319061110
Koyanagi-Aoi M., Ohnuki M., Takahashi K., Okita K., Noma H., Sawamura Y., Teramoto I., Narita M., Sato Y., Ichisaka T., Amano N., Watanabe A., Morizane A., Yamada Y., Sato T., Takahashi J., Yamanaka S.
Differentiation-defective phenotypes revealed by large-scale analyses of human pluripotent stem cells.
Proc. Natl. Acad. Sci. U.S.A. 110:20569-20574(2013)

PubMed=27476965; DOI=10.1016/j.stem.2016.06.019
Nishizawa M., Chonabayashi K., Nomura M., Tanaka A., Nakamura M., Inagaki A., Nishikawa M., Takei I., Oishi A., Tanabe K., Ohnuki M., Yokota H., Koyanagi-Aoi M., Okita K., Watanabe A., Takaori-Kondo A., Yamanaka S., Yoshida Y.
Epigenetic variation between human induced pluripotent stem cell lines is an indicator of differentiation capacity.
Cell Stem Cell 19:341-354(2016)

PubMed=33059130; DOI=10.1016/j.scr.2020.102020
Kawase E., Takada K., Suemori H.
Kyoto hESC cell resource for regenerative medicine.
Stem Cell Res. 49:102020-102020(2020)

PubMed=33225099; DOI=10.31662/jmaj.2018-0029
Umezawa A., Sato Y., Kusakawa S., Amagase R., Akutsu H., Nakamura K., Kasahara M., Matsubara Y., Igarashi T.
Research and development strategy for future embryonic stem cell- based therapy in Japan.
JMA J. 3:287-294(2020)

Cross-references
Cell line collections RCB; HES0001
Cell line databases/resources hPSCreg; KUIMSe001-A
ISCR; 550
SKIP; SKIP000147 - Discontinued
SKIP; SKIP001952
Encyclopedic resources Wikidata; Q54899868
Gene expression databases GEO; GSM1040238
GEO; GSM1040308
GEO; GSM1489246
GEO; GSM1489457
Entry history
Entry creation06-Jun-2012
Last entry update17-Mar-2022
Version number14