ID   KhES-1
AC   CVCL_B231
SY   KHES-1; KhES1; KUIMSe001-A
DR   GEO; GSM1040238
DR   GEO; GSM1040308
DR   GEO; GSM1489246
DR   GEO; GSM1489457
DR   hPSCreg; KUIMSe001-A
DR   ISCR; 550
DR   RCB; HES0001
DR   SKIP; SKIP000147
DR   SKIP; SKIP001952
DR   Wikidata; Q54899868
RX   PubMed=17572666;
RX   PubMed=21460823;
RX   PubMed=22802639;
RX   PubMed=24259714;
RX   PubMed=27476965;
RX   PubMed=33059130;
RX   PubMed=33225099;
WW   https://grants.nih.gov/stem_cells/registry/pending.htm
WW   http://www.nbrp.jp/report/reportProjectEn.jsp?project=esCell
CC   From: Institute for Frontier Medical Sciences, Kyoto University; Kyoto; Japan.
CC   Registration: NIH Human Embryonic Stem Cell Registry; pending review.
CC   Omics: DNA methylation analysis.
CC   Omics: Transcriptome analysis.
CC   Discontinued: SKIP; SKIP000147; probable.
OX   NCBI_TaxID=9606; ! Homo sapiens
SX   Female
AG   Blastocyst stage
CA   Embryonic stem cell
DT   Created: 06-06-12; Last updated: 17-03-22; Version: 14
//
RX   PubMed=17572666; DOI=10.1038/nbt1318;
RA   Adewumi O., Aflatoonian B., Ahrlund-Richter L., Amit M., Andrews P.W.,
RA   Beighton G., Bello P.A., Benvenisty N., Berry L.S., Bevan S., Blum B.,
RA   Brooking J., Chen K.G., Choo A.B.H., Churchill G.A., Corbel M.,
RA   Damjanov I., Draper J.S., Dvorak P., Emanuelsson K., Fleck R.A.,
RA   Ford A., Gertow K., Gertsenstein M., Gokhale P.J., Hamilton R.S.,
RA   Hampl A., Healy L.E., Hovatta O., Hyllner J., Imreh M.P.,
RA   Itskovitz-Eldor J., Jackson J., Johnson J.L., Jones M., Kee K.,
RA   King B.L., Knowles B.B., Lako M., Lebrin F., Mallon B.S., Manning D.,
RA   Mayshar Y., McKay R.D.G., Michalska A.E., Mikkola M., Mileikovsky M.,
RA   Minger S.L., Moore H.D., Mummery C.L., Nagy A., Nakatsuji N.,
RA   O'Brien C.M., Oh S.K.W., Olsson C., Otonkoski T., Park K.-Y.,
RA   Passier R., Patel H., Patel M., Pedersen R., Pera M.F.,
RA   Piekarczyk M.S., Pera R.A.R., Reubinoff B.E., Robins A.J., Rossant J.,
RA   Rugg-Gunn P., Schulz T.C., Semb H., Sherrer E.S., Siemen H.,
RA   Stacey G.N., Stojkovic M., Suemori H., Szatkiewicz J., Turetsky T.,
RA   Tuuri T., van den Brink S., Vintersten K., Vuoristo S., Ward D.,
RA   Weaver T.A., Young L.A., Zhang W.-D.;
RT   "Characterization of human embryonic stem cell lines by the
RT   International Stem Cell Initiative.";
RL   Nat. Biotechnol. 25:803-816(2007).
//
RX   PubMed=21460823; DOI=10.1038/nmeth.1591;
RA   Okita K., Matsumura Y., Sato Y., Okada A., Morizane A., Okamoto S.,
RA   Hong H., Nakagawa M., Tanabe K., Tezuka K., Shibata T., Kunisada T.,
RA   Takahashi M., Takahashi J., Saji H., Yamanaka S.;
RT   "A more efficient method to generate integration-free human iPS
RT   cells.";
RL   Nat. Methods 8:409-412(2011).
//
RX   PubMed=22802639; DOI=10.1073/pnas.1209979109;
RA   Kajiwara M., Aoi T., Okita K., Takahashi R., Inoue H., Takayama N.,
RA   Endo H., Eto K., Toguchida J., Uemoto S., Yamanaka S.;
RT   "Donor-dependent variations in hepatic differentiation from
RT   human-induced pluripotent stem cells.";
RL   Proc. Natl. Acad. Sci. U.S.A. 109:12538-12543(2012).
//
RX   PubMed=24259714; DOI=10.1073/pnas.1319061110;
RA   Koyanagi-Aoi M., Ohnuki M., Takahashi K., Okita K., Noma H.,
RA   Sawamura Y., Teramoto I., Narita M., Sato Y., Ichisaka T., Amano N.,
RA   Watanabe A., Morizane A., Yamada Y., Sato T., Takahashi J.,
RA   Yamanaka S.;
RT   "Differentiation-defective phenotypes revealed by large-scale analyses
RT   of human pluripotent stem cells.";
RL   Proc. Natl. Acad. Sci. U.S.A. 110:20569-20574(2013).
//
RX   PubMed=27476965; DOI=10.1016/j.stem.2016.06.019;
RA   Nishizawa M., Chonabayashi K., Nomura M., Tanaka A., Nakamura M.,
RA   Inagaki A., Nishikawa M., Takei I., Oishi A., Tanabe K., Ohnuki M.,
RA   Yokota H., Koyanagi-Aoi M., Okita K., Watanabe A., Takaori-Kondo A.,
RA   Yamanaka S., Yoshida Y.;
RT   "Epigenetic variation between human induced pluripotent stem cell
RT   lines is an indicator of differentiation capacity.";
RL   Cell Stem Cell 19:341-354(2016).
//
RX   PubMed=33059130; DOI=10.1016/j.scr.2020.102020;
RA   Kawase E., Takada K., Suemori H.;
RT   "Kyoto hESC cell resource for regenerative medicine.";
RL   Stem Cell Res. 49:102020-102020(2020).
//
RX   PubMed=33225099; DOI=10.31662/jmaj.2018-0029;
RA   Umezawa A., Sato Y., Kusakawa S., Amagase R., Akutsu H., Nakamura K.,
RA   Kasahara M., Matsubara Y., Igarashi T.;
RT   "Research and development strategy for future embryonic stem cell-
RT   based therapy in Japan.";
RL   JMA J. 3:287-294(2020).
//