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Cellosaurus S2/TXT (CVCL_B283)

Cell line name S2/TXT
Accession CVCL_B283
Resource Identification Initiative To cite this cell line use: S2/TXT (RRID:CVCL_B283)
Comments Selected for resistance to: ChEBI; CHEBI:4672; Docetaxel anhydrous (Taxotere).
Sequence variations CDKN2A p.Glu69Ter (c.205G>T) (p.Gly83Val; c.248G>T) (from parent cell line).
KRAS p.Gly12Asp (c.35G>A) (from parent cell line).
TP53 p.Arg273His (c.818G>A) (from parent cell line).
Disease Pancreatic ductal adenocarcinoma (NCIt: C9120)
Derived from metastatic site: Liver.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_3172 (SUIT-2)
Sex of cell Male
Age at sampling 73Y
Category Cancer cell line

PubMed=11819752; DOI=10.3748/wjg.v7.i1.143
Liu B., Staren E., Iwamura T., Appert H., Howard J.
Effects of taxotere on invasive potential and multidrug resistance phenotype in pancreatic carcinoma cell line SUIT-2.
World J. Gastroenterol. 7:143-148(2001)

PubMed=11854916; DOI=10.3748/wjg.v7.i6.855
Liu B., Staren E., Iwamura T., Appert H., Howard J.
Taxotere resistance in SUIT. Taxotere resistance in pancreatic carcinoma cell line SUIT 2 and its sublines.
World J. Gastroenterol. 7:855-859(2001)

Other Wikidata; Q54951876