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Cellosaurus HPAF (CVCL_B284)

Cell line name HPAF
Synonyms HPAF-I
Accession CVCL_B284
Resource Identification Initiative To cite this cell line use: HPAF (RRID:CVCL_B284)
Comments Sequence variation: KRAS p.Gly12Asp (PubMed=8026879).
Sequence variation: TP53 p.Pro151Ser (PubMed=8026879).
Disease Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
Sex of cell Male
Category Cancer cell line

Metzgar R.S., Gaillard M.T., Levine S.J., Tuck F.L., Bossen E.H., Borowitz M.J.
Antigens of human pancreatic adenocarcinoma cells defined by murine monoclonal antibodies.
Cancer Res. 42:601-608(1982)

PubMed=8026879; DOI=10.1002/ijc.2910580207
Berrozpe G., Schaeffer J., Peinado M.A., Real F.X., Perucho M.
Comparative analysis of mutations in the p53 and K-ras genes in pancreatic cancer.
Int. J. Cancer 58:185-191(1994)

PubMed=11169957; DOI=10.1002/1097-0215(200002)9999:9999<::AID-IJC1014>3.0.CO;2-U
Wallrapp C., Hahnel S., Boeck W., Soder A., Mincheva A., Lichter P., Leder G., Gansauge F., Sorio C., Scarpa A., Gress T.M.
Loss of the Y chromosome is a frequent chromosomal imbalance in pancreatic cancer and allows differentiation to chronic pancreatitis.
Int. J. Cancer 91:340-344(2001)

Polymorphism and mutation databases Cosmic; 724640
Cosmic; 736274
Cosmic; 808174
Cosmic; 872999
Cosmic; 922245
Cosmic; 933527
Cosmic; 948376
Cosmic; 948735