Cellosaurus logo
expasy logo

Cellosaurus MC-38 (CVCL_B288)

[Text version]
Cell line name MC-38
Synonyms MCA-38; MCA 38; MCA38; MC38; Mouse Colon 38; Murine Carcinoma-38; Colon 38; Colon-38; Colon38; C38
Accession CVCL_B288
Resource Identification Initiative To cite this cell line use: MC-38 (RRID:CVCL_B288)
Comments Omics: Mitochondrial genome sequenced.
Omics: SNP array analysis.
Caution: The authors of PubMed=25434994 indicate that they have sequenced the mitochondrial genome of the 'rat' cell line MCA38. Their submitted DNA sequence (KM820832.1) is indeed a rat sequence but is labelled as originating from 'rat isolate 406'.
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Disease Mouse colon adenocarcinoma (NCIt: C120044)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Hierarchy Children:
CVCL_D0P4 (MC-38 B2m-KO)CVCL_5I36 (MC-38-CEA-1)CVCL_5I37 (MC-38-CEA-2)
CVCL_5I38 (MC-38-MUC-1)CVCL_XZ58 (MC38 human PDL1)CVCL_B7NL (MC38-hPD-L1)
CVCL_C8VZ (MC38-Luc)CVCL_B7NQ (MC38-Luc-RFP)CVCL_B7NM (MC38-PD-L1 KO)
CVCL_XJ96 (MC38-OVA)CVCL_0A68 (MC38/0)CVCL_0A67 (MC38Luc1)
CVCL_B9CM (MC38Luc4)CVCL_B9CN (MC38Luc8)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): Ubigene

Markers:
Mouse STR 4-220.3
Mouse STR 5-516,17
Mouse STR 6-418
Mouse STR 6-715,16
Mouse STR 12-117
Mouse STR 15-322.3,23.3
Mouse STR 18-315,16
Mouse STR X-127

Run an STR similarity search on this cell line
Publications

PubMed=1149045
Corbett T.H., Griswold D.P. Jr., Roberts B.J., Peckham J.C., Schabel F.M. Jr.
Tumor induction relationships in development of transplantable cancers of the colon in mice for chemotherapy assays, with a note on carcinogen structure.
Cancer Res. 35:2434-2439(1975)

PubMed=1255804; DOI=10.1093/jnci/56.4.871
Tan M.H., Holyoke E.D., Goldrosen M.H.
Murine colon adenocarcinomas: methods for selective culture in vitro.
J. Natl. Cancer Inst. 56:871-873(1976)

PubMed=25277546; DOI=10.1186/1471-2164-15-847
Didion J.P., Buus R.J., Naghashfar Z., Threadgill D.W., Morse H.C. III, Pardo-Manuel de Villena F.
SNP array profiling of mouse cell lines identifies their strains of origin and reveals cross-contamination and widespread aneuploidy.
BMC Genomics 15:847.1-847.11(2014)

PubMed=25434994; DOI=10.3109/19401736.2014.974176
Zhang C.-F., Yu X.-J., Wang B.-Y., Chen H.-W., Hu C.-E.
Whole mitochondrial genome sequence of a rat colorectal cancer MCA38 cell line.
Mitochondrial DNA 27:2034-2035(2016)

Cross-references
Cell line collections (Providers) Kerafast; ENH204-FP
Ubigene; YC-A002
Cell line databases/resources CCRID; 1101MOU-PUMC000523
Lonza; 893
Anatomy/cell type resources BTO; BTO:0004163
Chemistry resources ChEMBL-Cells; CHEMBL3307696
ChEMBL-Targets; CHEMBL612821
PubChem_Cell_line; CVCL_B288
Encyclopedic resources Wikidata; Q54904168
Entry history
Entry creation06-Jun-2012
Last entry update05-Oct-2023
Version number21