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Cellosaurus MC-38 (CVCL_B288)

[Text version]

Cell line name MC-38
Synonyms MCA-38; MCA 38; MCA38; MC38; Mouse Colon 38; Murine Carcinoma-38; Colon 38; Colon-38; Colon38; C38
Accession CVCL_B288
Resource Identification Initiative To cite this cell line use: MC-38 (RRID:CVCL_B288)
Comments Omics: Mitochondrial genome sequenced.
Omics: SNP array analysis.
Caution: The authors of PubMed=25434994 indicate that they have sequenced the mitochondrial genome of the 'rat' cell line MCA38. Their submitted DNA sequence (KM820832.1) is indeed a rat sequence but is labelled as originating from 'rat isolate 406'.
Disease Mouse colon adenocarcinoma (NCIt: C120044)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Hierarchy Children:
CVCL_5I36 (MC-38-CEA-1)CVCL_5I37 (MC-38-CEA-2)CVCL_5I38 (MC-38-MUC-1)
CVCL_0A68 (MC38/0)CVCL_0A67 (MC38Luc1)
Sex of cell Female
Category Cancer cell line
Web pages https://www.kerafast.com/product/2720/mc-38-cell-line

Corbett T.H., Griswold D.P. Jr., Roberts B.J., Peckham J.C., Schabel F.M. Jr.
Tumor induction relationships in development of transplantable cancers of the colon in mice for chemotherapy assays, with a note on carcinogen structure.
Cancer Res. 35:2434-2439(1975)

PubMed=1255804; DOI=10.1093/jnci/56.4.871
Tan M.H., Holyoke E.D., Goldrosen M.H.
Murine colon adenocarcinomas: methods for selective culture in vitro.
J. Natl. Cancer Inst. 56:871-873(1976)

PubMed=25277546; DOI=10.1186/1471-2164-15-847
Didion J.P., Buus R.J., Naghashfar Z., Threadgill D.W., Morse H.C. III, de Villena F.P.
SNP array profiling of mouse cell lines identifies their strains of origin and reveals cross-contamination and widespread aneuploidy.
BMC Genomics 15:847-847(2014)

PubMed=25434994; DOI=10.3109/19401736.2014.974176
Zhang C.-F., Yu X.-J., Wang B.-Y., Chen H.-W., Hu C.-E.
Whole mitochondrial genome sequence of a rat colorectal cancer MCA38 cell line.
Mitochondrial DNA 27:2034-2035(2016)

Cell line databases/resources Lonza; 893
Ontologies BTO; BTO:0004163
Chemistry resources ChEMBL-Cells; CHEMBL3307696
ChEMBL-Targets; CHEMBL612821
Other Wikidata; Q54904168
Entry history
Entry creation06-Jun-2012
Last entry updated07-Sep-2018
Version number14