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Cellosaurus DR-EcoScreen-HS (CVCL_B3MB)

[Text version]
Cell line name DR-EcoScreen-HS
Accession CVCL_B3MB
Resource Identification Initiative To cite this cell line use: DR-EcoScreen-HS (RRID:CVCL_B3MB)
Comments Biotechnology: Used in a bioassay for the determination of polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) and dioxin-like polychlorinated biphenyls (DL-PCBs) in environmental and food samples.
Characteristics: Acts through the activation of a luciferase reporter gene under the control of dioxin-response elements (DREs).
Characteristics: Has higher responsiveness to TCDD than DR-EcoScreen (JCRB=JCRB1853).
Transfected with: UniProtKB; P08659; Firefly luciferase.
Transfected with: UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Disease Hepatocellular carcinoma of the mouse (NCIt: C38756)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57L.
Hierarchy Parent: CVCL_0328 (Hepa-1c1c7)
Sex of cell Female
Category Cancer cell line
Cross-references
Cell line collections (Providers) JCRB; JCRB1853
Encyclopedic resources Wikidata; Q110432778
Entry history
Entry creation16-Dec-2021
Last entry update05-Oct-2023
Version number7