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Cellosaurus Rag2-/- pro-B cells (CVCL_B3QD)

[Text version]
Cell line name Rag2-/- pro-B cells
Synonyms RAG2KO pro-B cells
Accession CVCL_B3QD
Resource Identification Initiative To cite this cell line use: Rag2-/- pro-B cells (RRID:CVCL_B3QD)
Comments Characteristics: Rag2-/- pro-B cells maintained on OP42 stromal cells.
Knockout cell: Method=KO mouse; MGI; MGI:97849; Rag2.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: Pro-B cell; CL=CL_0000826.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: 129S6/SvEvTac-Rag2tm1Fwa.
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Finite cell line
Publications

PubMed=16025120; DOI=10.1038/ni1226
Bertolino E., Reddy K.L., Medina K.L., Parganas E., Ihle J.N., Singh H.
Regulation of interleukin 7-dependent immunoglobulin heavy-chain variable gene rearrangements by transcription factor STAT5.
Nat. Immunol. 6:836-843(2005)

PubMed=18176567; DOI=10.1038/ni1555
Pongubala J.M.R., Northrup D.L., Lancki D.W., Medina K.L., Treiber T., Bertolino E., Thomas M., Grosschedl R., Allman D., Singh H.
Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5.
Nat. Immunol. 9:203-215(2008)

PubMed=20971928; DOI=10.4049/jimmunol.0904203
Gwin K., Frank E., Bossou A.R., Medina K.L.
Hoxa9 regulates Flt3 in lymphohematopoietic progenitors.
J. Immunol. 185:6572-6583(2010)

Cross-references
Encyclopedic resources Wikidata; Q110433158
Entry history
Entry creation16-Dec-2021
Last entry update29-Jun-2023
Version number4