Home  |  Contact

Cellosaurus NPLC/PRF/5 (CVCL_B449)

[Text version]

Cell line name NPLC/PRF/5
Synonyms N-PLC/PRF/5
Accession CVCL_B449
Resource Identification Initiative To cite this cell line use: NPLC/PRF/5 (RRID:CVCL_B449)
Comments Population: African; Shangaan.
Karyotypic information: Has lost chromosome Y.
Transformant: NCBI_TaxID; 10407; Hepatitis B virus (HBV).
Derived from sampling site: Liver.
Sequence variations Mutation; HGNC; 1787; CDKN2A; Simple; p.Arg112Gly (c.334C>G) (p.Pro126Arg, c.377C>G); ClinVar=VCV000233484; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; 11998; TP53; Simple; p.Arg249Ser (c.747G>T); ClinVar=VCV000012352; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; 12363; TSC2; Simple; p.Asn1651Ser (c.4952A>G); ClinVar=VCV000049335; Zygosity=Homozygous (from parent cell line).
Disease Adult hepatocellular carcinoma (NCIt: C7956)
Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0485 (PLC/PRF/5)
Sex of cell Male
Age at sampling 24Y
Category Cancer cell line

PubMed=2827003; DOI=10.1128/MCB.8.1.25
Carlin C.R., Simon D., Mattison J., Knowles B.B.
Expression and biosynthetic variation of the epidermal growth factor receptor in human hepatocellular carcinoma-derived cell lines.
Mol. Cell. Biol. 8:25-34(1988)

Ontologies BTO; BTO:0002906
Other Wikidata; Q54930996
Entry history
Entry creation06-Jun-2012
Last entry update20-May-2021
Version number14