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Cellosaurus SU-CCS-1 (CVCL_B470)

Cell line name SU-CCS-1
Synonyms Su-ccs-1; Su CCS-1; SU-CCS1; SUCCS1
Accession CVCL_B470
Resource Identification Initiative To cite this cell line use: SU-CCS-1 (RRID:CVCL_B470)
Comments Population: Caucasian.
Doubling time: ~52 hours (PubMed=6362860).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene fusion; HGNC; 783; ATF1 + HGNC; 3508; EWSR1; Name(s)=EWSR1-ATF1, EWS-ATF (PubMed=7753552; PubMed=15150091).
Disease Clear cell sarcoma of soft tissue (NCIt: C3745)
Soft tissue sarcoma (ORDO: Orphanet_3394)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 16Y
Category Cancer cell line
STR profile Source(s): ATCC

Markers:
AmelogeninX
CSF1PO10,11
D5S81812,14
D7S82012
D13S3178
D16S53911
TH016,7
TPOX8,11
vWA16,17

Run an STR similarity search on this cell line
Publications

PubMed=6362860
Epstein A.L., Martin A.O., Kempson R.
Use of a newly established human cell line (SU-CCS-1) to demonstrate the relationship of clear cell sarcoma to malignant melanoma.
Cancer Res. 44:1265-1274(1984)

PubMed=7753552
Brown A.D., Lopez-Terrada D.H., Denny C., Lee K.A.W.
Promoters containing ATF-binding sites are de-regulated in cells that express the EWS/ATF1 oncogene.
Oncogene 10:1749-1756(1995)

PubMed=12966428; DOI=10.1038/sj.bjc.6601212
Li K.K.C., Goodall J., Goding C.R., Liao S.-K., Wang C.-H., Lin Y.-C., Hiraga H., Nojima T., Nagashima K., Schaefer K.-L., Lee K.A.W.
The melanocyte inducing factor MITF is stably expressed in cell lines from human clear cell sarcoma.
Br. J. Cancer 89:1072-1078(2003)

PubMed=15150091; DOI=10.1158/0008-5472.CAN-03-0809
Schaefer K.-L., Brachwitz K., Wai D.H., Braun Y., Diallo R., Korsching E., Eisenacher M., Voss R., van Valen F., Baer C., Selle B., Spahn L., Liao S.-K., Lee K.A.W., Hogendoorn P.C.W., Reifenberger G., Gabbert H.E., Poremba C.
Expression profiling of t(12;22) positive clear cell sarcoma of soft tissue cell lines reveals characteristic up-regulation of potential new marker genes including ERBB3.
Cancer Res. 64:3395-3405(2004)

PubMed=16766266; DOI=10.1016/j.ccr.2006.04.021
Davis I.J., Kim J.J., Ozsolak F., Widlund H.R., Rozenblatt-Rosen O., Granter S.R., Du J.-Y., Fletcher J.A., Denny C.T., Lessnick S.L., Linehan W.M., Kung A.L.-J., Fisher D.E.
Oncogenic MITF dysregulation in clear cell sarcoma: defining the MiT family of human cancers.
Cancer Cell 9:473-484(2006)

Cross-references
Cell line collections (Providers) ATCC; CRL-2971
Encyclopedic resources Wikidata; Q54970704
Polymorphism and mutation databases Cosmic; 1092866
Entry history
Entry creation06-Jun-2012
Last entry update05-Oct-2023
Version number14