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Cellosaurus OCUT-4 (CVCL_B5GB)

[Text version]
Cell line name OCUT-4
Synonyms Osaka City University Thyroid-4
Accession CVCL_B5GB
Resource Identification Initiative To cite this cell line use: OCUT-4 (RRID:CVCL_B5GB)
Comments Population: Japanese.
Derived from site: In situ; Thyroid gland; UBERON=UBERON_0002046.
Sequence variations
  • Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=24357248).
Disease Thyroid gland anaplastic carcinoma (NCIt: C3878)
Anaplastic thyroid carcinoma (ORDO: Orphanet_142)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 78Y
Category Cancer cell line
STR profile Source(s): JCRB=JCRB1857

Markers:
AmelogeninX,Y
CSF1PO12
D5S8189,11
D7S8208
D13S3178
D16S5399,12
TH019
TPOX8,9
vWA17,19

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Publications

PubMed=24357248; DOI=10.1007/s00268-013-2409-7
Onoda N., Nakamura M., Aomatsu N., Noda S., Kashiwagi S., Hirakawa K.
Establishment, characterization and comparison of seven authentic anaplastic thyroid cancer cell lines retaining clinical features of the original tumors.
World J. Surg. 38:688-695(2014)

PubMed=26137260; DOI=10.3892/mco.2015.496
Onoda N., Nakamura M., Aomatsu N., Noda S., Kashiwagi S., Kurata K., Uchino S., Hirakawa K.
Significant cytostatic effect of everolimus on a gefitinib-resistant anaplastic thyroid cancer cell line harboring PI3KCA gene mutation.
Mol. Clin. Oncol. 3:522-526(2015)

Cross-references
Cell line collections (Providers) JCRB; JCRB1857
Cell line databases/resources cancercelllines; CVCL_B5GB
Encyclopedic resources Wikidata; Q110433126
Entry history
Entry creation16-Dec-2021
Last entry update02-May-2024
Version number6