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Cellosaurus WA09 NRL+/eGFP (CVCL_B5ZI)

[Text version]

Cell line name WA09 NRL+/eGFP
Accession CVCL_B5ZI
Resource Identification Initiative To cite this cell line use: WA09 NRL+/eGFP (RRID:CVCL_B5ZI)
Comments Characteristics: Valuable tool for studying human rod development and disease and testing therapeutic strategies for retinitis pigmentosa (PubMed=29402929).
Characteristics: Using CRISPR/Cas9 a single allele of NRL was replaced with an eGFP reporter gene (PubMed=29402929).
Knockout cell: Method=CRISPR/Cas9 (1 of 2 alleles); HGNC; 8002; NRL.
Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_9773 (WA09)
Sex of cell Female
Age at sampling Blastocyst stage
Category Embryonic stem cell
Publications

PubMed=29402929; DOI=10.1038/s41598-018-20813-3
Phillips M.J., Capowski E.E., Petersen A., Jansen A.D., Barlow K., Edwards K.L., Gamm D.M.
Generation of a rod-specific NRL reporter line in human pluripotent stem cells.
Sci. Rep. 8:2370-2370(2018)

Cross-references
Encyclopedic resources Wikidata; Q112041918
Entry history
Entry creation17-Mar-2022
Last entry update23-Jun-2022
Version number2