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Cellosaurus Akata ZKO (CVCL_B6R6)

[Text version]
Cell line name Akata ZKO
Synonyms Akata/ZKO-EBV
Accession CVCL_B6R6
Resource Identification Initiative To cite this cell line use: Akata ZKO (RRID:CVCL_B6R6)
Comments Population: Japanese.
Virology: EBV-negative cell line re-infected with recombinant EBV whose genome is KO for BZLF1.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Pro190Leufs*57 (c.569delC); ClinVar=VCV000825904; Zygosity=Unspecified (from parent cell line).
Disease EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_VN89 (Akata-EBV-N)
Sex of cell Female
Age at sampling 4Y
Category Cancer cell line
STR profile Source(s): JCRB

Markers:
AmelogeninX
CSF1PO11
D5S81811,12
D7S82010,12
D13S3178,12
D16S53910,11
TH019
TPOX8,11
vWA14,16

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Publications

PubMed=19553389; DOI=10.1099/vir.0.012831-0
Katsumura K.R., Maruo S., Wu Y., Kanda T., Takada K.
Quantitative evaluation of the role of Epstein-Barr virus immediate-early protein BZLF1 in B-cell transformation.
J. Gen. Virol. 90:2331-2341(2009)

Cross-references
Cell line collections (Providers) JCRB; JCRB1869
Encyclopedic resources Wikidata; Q111732904
Entry history
Entry creation17-Mar-2022
Last entry update29-Jun-2023
Version number5