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Cellosaurus MTA-13 (CVCL_B7N4)

[Text version]
Cell line name MTA-13
Accession CVCL_B7N4
Resource Identification Initiative To cite this cell line use: MTA-13 (RRID:CVCL_B7N4)
Comments Selected for resistance to: ChEBI; CHEBI:63616; Pemetrexed (Alimta; LY231514).
Transformant: ChEBI; CHEBI:34342; 3-methylcholanthrene (3-MC; 20-methylcholanthrene; 20-MC; MCA).
Transformant: ChEBI; CHEBI:23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Cell type: T-cell; CL=CL_0000084.
Disease Mouse leukemia (NCIt: C21604)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: DBA/2.
Hierarchy Parent: CVCL_0382 (L1210)
Sex of cell Female
Age at sampling 8M
Category Cancer cell line
Publications

PubMed=12663051; DOI=10.1016/s0006-2952(03)00007-8
Wang Y.-H., Zhao R.-B., Goldman I.D.
Decreased expression of the reduced folate carrier and folypolyglutamate synthetase is the basis for acquired resistance to the pemetrexed antifolate (LY231514) in an L1210 murine leukemia cell line.
Biochem. Pharmacol. 65:1163-1170(2003)

Cross-references
Encyclopedic resources Wikidata; Q112930130
Entry history
Entry creation23-Jun-2022
Last entry update05-Oct-2023
Version number5