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Cellosaurus RUES2 (CVCL_B810)

[Text version]
Cell line name RUES2
Synonyms Rockefeller University Embryonic Stem cell line 2; RUESe002-A
Accession CVCL_B810
Resource Identification Initiative To cite this cell line use: RUES2 (RRID:CVCL_B810)
Comments From: Rockefeller University; New York; USA.
Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-10-0013.
Registration: Swiss research registry; BAG-hES-IMP-0057.
Omics: Array-based CGH.
Omics: Deep exome analysis.
Omics: SNP array analysis.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_VM28 (RUES2 HOPX KO)CVCL_VM29 (RUES2 HOPX-tdTomato)CVCL_WN79 (RUES2 SFTPC-tdTomato)
CVCL_IQ87 (RUES2-EGFP/SMAD7)CVCL_C1W2 (RUESe002-A-1)CVCL_C1W3 (RUESe002-A-2)
CVCL_C1W4 (RUESe002-A-4)CVCL_C1W5 (RUESe002-A-5)
Sex of cell Female
Age at sampling Blastocyst stage
Category Embryonic stem cell
STR profile Source(s): WiCell

Markers:
AmelogeninX
CSF1PO11
D3S135814,15
D5S81811,12
D7S82012,13
D8S117910,13
D13S31711
D16S53912,15
D18S5116,18
D21S1129
FGA22,25
Penta D9,12
Penta E13,14
TH017,9.3
TPOX8
vWA16

Run an STR similarity search on this cell line
Web pages http://rues.rockefeller.edu/rues2.html
Publications

PubMed=28445466; DOI=10.1038/nature22312
Merkle F.T., Ghosh S., Kamitaki N., Mitchell J., Avior Y., Mello C., Kashin S., Mekhoubad S., Ilic D., Charlton M., Saphier G., Handsaker R.E., Genovese G., Bar S., Benvenisty N., McCarroll S.A., Eggan K.C.
Human pluripotent stem cells recurrently acquire and expand dominant negative P53 mutations.
Nature 545:229-233(2017)

PubMed=35805069; DOI=10.3390/cells11131984
Molina-Ruiz F.J., Introna C., Bombau G., Galofre M., Canals J.M.
Standardization of cell culture conditions and routine genomic screening under a quality management system leads to reduced genomic instability in hPSCs.
Cells 11:1984.1-1984.25(2022)

Cross-references
Cell line collections (Providers) WiCell; rues2
Cell line databases/resources hPSCreg; RUESe002-A
ISCR; 682
NIHhESC; NIHhESC-10-0013
Biological sample resources 4DN; 4DNSR2VQCV9W
BioSamples; SAMEA104387770
ENCODE; ENCBS089ZVW
Encyclopedic resources Wikidata; Q54951469
Experimental variables resources EFO; EFO_0009320
Entry history
Entry creation06-Jun-2012
Last entry update29-Jun-2023
Version number21