ID   CyT49
AC   CVCL_B850
SY   VCYTe001-A
DR   EFO; EFO_0007073
DR   BioSamples; SAMEA17469418
DR   ENCODE; ENCBS882LFH
DR   ENCODE; ENCBS976TXC
DR   GEO; GSM1548607
DR   GEO; GSM1548608
DR   hPSCreg; VCYTe001-A
DR   ISCR; 702
DR   NIHhESC; NIHhESC-10-0041
DR   SKIP; SKIP002593
DR   Wikidata; Q54817112
RX   PubMed=18288110;
RX   PubMed=22623968;
RX   PubMed=28445466;
WW   https://discovery.lifemapsc.com/stem-cell-differentiation/in-vitro-cells/inner-cell-mass-homo-sapiens-cyt49-viacyte-novocell-san-diego-ca
CC   From: ViaCyte, Inc. (originally from CyThera, Novocell); San Diego; USA.
CC   Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-10-0041.
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Gly245Cys (c.733G>T); ClinVar=VCV000012349; Zygosity=Unspecified; Note=Somatic mutation acquired during proliferation (PubMed=28445466).
CC   Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
CC   Cell type: Embryonic stem cell; CL=CL_0002322.
ST   Source(s): Novocell
ST   CSF1PO: 11,12
ST   D13S317: 11,12
ST   D16S539: 9,12
ST   D18S51: 12,18
ST   D21S11: 28
ST   D3S1358: 16,17
ST   D5S818: 10,11
ST   D7S820: 10,12
ST   D8S1179: 12,16
ST   FGA: 21,23
ST   Penta E: 17,20
ST   TH01: 9.3
ST   TPOX: 8,9
ST   vWA: 16,17
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   Blastocyst stage
CA   Embryonic stem cell
DT   Created: 06-06-12; Last updated: 30-01-24; Version: 20
//
RX   PubMed=18288110; DOI=10.1038/nbt1393;
RA   Kroon E.J., Martinson L.A., Kadoya K., Bang A.G., Kelly O.G.,
RA   Eliazer S., Young H.Y., Richardson M., Smart N.G., Cunningham J.,
RA   Agulnick A.D., D'Amour K.A., Carpenter M.K., Baetge E.E.;
RT   "Pancreatic endoderm derived from human embryonic stem cells generates
RT   glucose-responsive insulin-secreting cells in vivo.";
RL   Nat. Biotechnol. 26:443-452(2008).
//
RX   PubMed=22623968; DOI=10.1371/journal.pone.0037004;
RA   Schulz T.C., Young H.Y., Agulnick A.D., Babin M.J., Baetge E.E.,
RA   Bang A.G., Bhoumik A., Cepa I., Cesario R.M., Haakmeester C.,
RA   Kadoya K., Kelly J.R., Kerr J., Martinson L.A., McLean A.B.,
RA   Moorman M.A., Payne J.K., Richardson M., Ross K.G., Sherrer E.S.,
RA   Song X.-H., Wilson A.Z., Brandon E.P., Green C.E., Kroon E.J.,
RA   Kelly O.G., D'Amour K.A., Robins A.J.;
RT   "A scalable system for production of functional pancreatic progenitors
RT   from human embryonic stem cells.";
RL   PLoS ONE 7:E37004-E37004(2012).
//
RX   PubMed=28445466; DOI=10.1038/nature22312;
RA   Merkle F.T., Ghosh S., Kamitaki N., Mitchell J., Avior Y., Mello C.,
RA   Kashin S., Mekhoubad S., Ilic D., Charlton M., Saphier G.,
RA   Handsaker R.E., Genovese G., Bar S., Benvenisty N., McCarroll S.A.,
RA   Eggan K.C.;
RT   "Human pluripotent stem cells recurrently acquire and expand dominant
RT   negative P53 mutations.";
RL   Nature 545:229-233(2017).
//