ID   ESI-049
AC   CVCL_B857
SY   ESI049; SSCCe004-A
DR   hPSCreg; SSCCe004-A
DR   ISCR; 82
DR   SKIP; SKIP002088
DR   Wikidata; Q54832759
RX   PubMed=18371388;
RX   PubMed=20177998;
RX   PubMed=22265736;
RX   PubMed=28445466;
WW   http://www.esibio.com/products/product-category/cell-lines/esi-049-human-embryonic-stem-cell-line-46-xy/
WW   https://grants.nih.gov/stem_cells/registry/current.htm?id=486
CC   Group: Clinical grade hESC cell line.
CC   From: ESI BIO - BioTime, Inc. (ES Cell International).
CC   Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-11-0130.
CC   Omics: CNV analysis.
CC   Omics: Deep exome analysis.
CC   Omics: Genome sequenced.
CC   Omics: SNP array analysis.
ST   Source(s): ESI_BIO
ST   Amelogenin: X,Y
ST   CSF1PO: 10,12
ST   D13S317: 12,13
ST   D16S539: 9,11
ST   D18S51: 10,13
ST   D21S11: 29,31
ST   D3S1358: 15,16
ST   D5S818: 11,12
ST   D7S820: 11,13
ST   D8S1179: 14,15
ST   FGA: 18,20
ST   Penta D: 11,15
ST   Penta E: 15,18
ST   TH01: 9
ST   TPOX: 8,11
ST   vWA: 17,19
OX   NCBI_TaxID=9606; ! Homo sapiens
SX   Male
AG   Blastocyst stage
CA   Embryonic stem cell
DT   Created: 06-06-12; Last updated: 07-09-18; Version: 13
//
RX   PubMed=18371388; DOI=10.1016/j.stem.2007.10.004;
RA   Crook J.M., Peura T.T., Kravets L., Bosman A.G., Buzzard J.J.,
RA   Horne R., Hentze H., Dunn N.R., Zweigerdt R., Chua F., Upshall A.,
RA   Colman A.;
RT   "The generation of six clinical-grade human embryonic stem cell
RT   lines.";
RL   Cell Stem Cell 1:490-494(2007).
//
RX   PubMed=20177998; DOI=10.1007/s11626-010-9287-1;
RA   Sivarajah S., Raj G.S., Mathews A.J., Sahib N.B., Hwang W.-S.,
RA   Crook J.M.;
RT   "The generation of GLP-grade human embryonic stem cell banks from four
RT   clinical-grade cell lines for preclinical research.";
RL   In Vitro Cell. Dev. Biol. Anim. 46:210-216(2010).
//
RX   PubMed=22265736; DOI=10.1016/j.scr.2011.10.001;
RA   Funk W.D., Labat I., Sampathkumar J., Gourraud P.A., Oksenberg J.R.,
RA   Rosler E.S., Steiger D., Sheibani N., Caillier S., Stache-Crain B.,
RA   Johnson J.A., Meisner L., Lacher M.D., Chapman K.B., Park M.J.,
RA   Shin K.-J., Drmanac R., West M.D.;
RT   "Evaluating the genomic and sequence integrity of human ES cell lines;
RT   comparison to normal genomes.";
RL   Stem Cell Res. 8:154-164(2012).
//
RX   PubMed=28445466; DOI=10.1038/nature22312;
RA   Merkle F.T., Ghosh S., Kamitaki N., Mitchell J., Avior Y., Mello C.,
RA   Kashin S., Mekhoubad S., Ilic D., Charlton M., Saphier G.,
RA   Handsaker R.E., Genovese G., Bar S., Benvenisty N., McCarroll S.A.,
RA   Eggan K.;
RT   "Human pluripotent stem cells recurrently acquire and expand dominant
RT   negative P53 mutations.";
RL   Nature 545:229-233(2017).
//