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Cellosaurus MasterShef10 (CVCL_BW82)

[Text version]

Cell line name MasterShef10
Synonyms MasterShef 10; MstrShef10; MShef10; UOSe014-A
Accession CVCL_BW82
Resource Identification Initiative To cite this cell line use: MasterShef10 (RRID:CVCL_BW82)
Comments Group: Clinical grade hESC cell line.
From: University of Sheffield; Sheffield; UK.
Registration: UK Stem Cell Bank (UKSCB); Steering comm. appl. SCSC13-05.
Omics: CNV analysis.
Omics: Deep exome analysis.
Omics: SNP array analysis.
Sequence variations TP53 p.Gly245Ser (c.733G>A) (ClinVar=VCV000012365) and p.Arg248Trp (c.742C>T) (ClinVar=VCV000012347); somatic mutations acquired during proliferation (PubMed=28445466).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Blastocyst stage
Category Embryonic stem cell

PubMed=26607962; DOI=10.1038/srep17258
Canham M.A., Van Deusen A.L., Brison D.R., De Sousa P.A., Downie J.M., Devito L., Hewitt Z.A., Ilic D., Kimber S.J., Moore H.D., Murray H., Kunath T.
The molecular karyotype of 25 clinical-grade human embryonic stem cell lines.
Sci. Rep. 5:17258-17258(2015)

PubMed=28445466; DOI=10.1038/nature22312
Merkle F.T., Ghosh S., Kamitaki N., Mitchell J., Avior Y., Mello C., Kashin S., Mekhoubad S., Ilic D., Charlton M., Saphier G., Handsaker R.E., Genovese G., Bar S., Benvenisty N., McCarroll S.A., Eggan K.
Human pluripotent stem cells recurrently acquire and expand dominant negative P53 mutations.
Nature 545:229-233(2017)

Cell line databases/resources hPSCreg; UOSe014-A
Biological sample resources BioSamples; SAMEA104627967
Other Wikidata; Q54904041
Entry history
Entry creation13-Jul-2016
Last entry update02-Jul-2020
Version number8